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机构地区:[1]广西医科大学第一附属医院皮肤性病科,南宁530021 [2]广西医科大学第一附属医院西院急诊科,南宁530007 [3]广西医科大学第一附属医院生殖医学研究中心
出 处:《广西医科大学学报》2007年第6期846-848,共3页Journal of Guangxi Medical University
基 金:广西科技厅课题(桂科自0342032)
摘 要:目的:评价广西地区宫颈炎支原体感染患者临床治疗效果,为实际治疗提供依据。方法:样本328例取自我院门诊经病原学确诊的宫颈炎单纯支原体感染患者,随机分为3组,A组97例口服阿奇霉素0.5g/d,B组110例口服左氧氟沙星0.4g/d、C组121例依据药敏测定选择药物治疗,疗程为一周,停药一周后复查,以临床症状、阴道分泌物清洁度、宫颈炎症情况及宫颈分泌物支原体转阴等作为评价指标。结果:3组的临床症状、阴道分泌物清洁度、宫颈炎症程度、宫颈糜烂面大小及支原体转阴情况治疗后都有明显改变(P<0.01),C组疗效更好(P<0.05)。结论:经验性用药和根据药敏测定用药对妇女宫颈炎支原体感染都可取得较满意的治疗效果,根据药敏测定用药疗效更好。Objective: To estimate the curative effect of cervicitis patients in Guangxi area with mere mycoplasm infection, and give a suggestion for better curative effect. Methods: The selected 328 Guangxi cervicitis patients proved to be infected merely with mycoplasm at the beginning of our research of their vaginal secretions that were cultured and identified for mycoplasm, were randomly divided to three groups. Group A( n =97) was treated by azithromycin; Group B( n = 110) was treated by levofloxacin; Group C( n =121) was treated by the antibiotic which had been proved sensitive by drug sensitivity test. The treatment lasted for 1 week. After an other week the curative effect was compared by the changes in leucorrhea, cervix, and whether the mycoplasm were removed was confirmed. All data were proceeded statistically before the final conclusions. Result: All the three groups showed significant curative effect, with Goup C having significantly better curative effect. Conclusion: Azithromycin and levofloxacin are able to get satisfied cura- tive effect in the treatment for cervicitis patients with mere mycoplasm infection, meanwhile, to give that sensitive antibiotic which has been proved sensitive by test can get better curative effect.
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