泌尿系感染与手术切口感染相关性分析  

Relationship Between Urinary Tract Infection and Urological Surgical Site Infections

作　　者：叶林阳[1] 林茂虎[1] 郁华亮[1] 朱晓应[1] 苗芮[1] 贾宁[2] 

机构地区：[1]解放军总医院第一附属医院,北京100037 [2]解放军总医院,北京100853

出　　处：《中华医院感染学杂志》2007年第12期1512-1514,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助(30300296)

摘　　要：目的探讨泌尿系感染与手术切口感染的相关性。方法对115例泌尿外科手术感染进行观察,并对感染切口、手术缝合前皮下组织和术前患者尿液分离培养,检测分离菌对围手术期使用的二代头孢菌素头孢呋辛的敏感性和同源性。结果115例泌尿外科术后患者14例发生手术部位感染,手术切口部位感染分离出的病原菌对围手术期使用的二代头孢菌素耐药率高于未发生切口部位感染的分离菌(P<0.05);切口感染的患者术前泌尿系感染发生率高于未发生切口感染患者(P<0.05),分离菌株以葡萄球菌属居多,PFGE分析显示分离自同一患者的菌株多为同一菌株或同型不同亚型菌株。结论术前患者泌尿系感染是手术切口感染的重要危险因素。OBJECTIVE To explore the relationship between urinary tract infection（UTI） and urological surgical site infections（SSI）.METHODS The surgical site infections of 115 patients underwent urological operations were observed.Patients were screened for the presence of UTI before the operation and subcutaneous swabs for culture were collected at the end of the operation by brushing with a sterile cotton-swab just before skin closure.The resistance and similarity of the isolates were analyzed by antimicrobial susceptibility test and pulsed field gel electrophoresis（PFGE）.RESULTS Surgical site infection occurred in 14 of 115 patients.The isolates from infected surgical sites showed higher resistance to antimicrobial agents than those from non-infected surgical sites（P〈0.05）.The prevalence of UTI was higher in patients with SSI （P〈0.05）.The isolates from each one patient showed high similarity by PFGE.CONCLUSIONS Preoperative urinary tract infection is an important risk factor for SSI following urological operation.

关 键 词：泌尿系感染 手术部位 手术切口 围手术期 

分 类 号：R691.3[医药卫生—泌尿科学]