肺泡巨噬细胞对肺气虚证局部神经-内分泌-免疫系统功能影响  

Influence of Alveolar Macrophage from Patients with Pulmonary Qi Deficiency Syndrome on Neuro Endocrine Immune System

作　　者：宋卫东[1] 赵江云[1] 刘中本 吴华强 张安成[1] 庞玉英[1] 刘丽华[1] 

机构地区：[1]安徽医科大学第一附属医院呼吸内科

出　　处：《中国中医基础医学杂志》1997年第4期31-33,共3页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家自然科学基金;国家中医药管理局资助

摘　　要：检测４０例慢性支气管炎肺气虚证、３９例慢支隐性肺证患者及３６例正常人外周血、支气管肺灌洗液（ＢＡＬＦ）Ｔ淋巴细胞亚群（ＯＫＴ８）、皮质醇及去甲肾上腺素以及肺泡巨噬细胞（ＡＭ）分泌ＴＸＢ２／ＰＧＦ１ａ。结果表明：肺气虚证局部ＮＥＩＳ紊乱较明显，它与ＡＭ分泌的ＴＸＢ２和ＰＧＦ１ａ有关。隐性肺证局部病理生理变化较轻，局部与整体ＮＥＩＳ功能相互作用，尤其是整体对局部的调节稳定作有更加明显。Examing the levels of Cortisol (Cort), Noradrenalin (NE) and T lymphocyte population (OKT8) in serum, Bronchoalveolar Lavage Fluid (BALF) and TXB2, PGF1a secreted by Alveolar Macrophage (AM) from 40 COPD patients with Pulmonary Qi Deficiency Syndrome, 39 COPD patients with Recessive Pulmonary Syndrome and 36 normal subjects. Results showed that local disorder of NEIS was very obviously in the patients with Pulmonary Qi Deficiency Syndrome and related with TXB2/PGF1a secreted by AM. A little changes was found in local physiophathology from patients with Recessive Pulmonary Syndrome. The function of local and unity NEIS was correlated, specially unity of NEIS stably controlled local NEIS obviously, so it was obviously decreased that factors of inflammation from patients with Recessive Pulmonary Syndrome destroied the local NEIS.

关 键 词：肺气虚证 肺泡巨噬细胞 病理 

分 类 号：R256.102[医药卫生—中医内科学]