氧合功能指标监测在新生儿呼吸衰竭时的临床应用价值  

Clinical significance of monitoring indexes of oxygen function in neonate with respiratory failure

作　　者：黄育丹[1] 瞿尔力[1] 邓秀睿[1] 陈清[1] 苏卫东[1] 

机构地区：[1]浙江省温州市第二人民医院新生儿科,温州325000

出　　处：《临床医学》2008年第1期32-33,共2页Clinical Medicine

摘　　要：目的探讨新生儿呼吸衰竭时氧合功能指标监测的临床意义。方法对在新生儿重症监护室中应用呼吸机治疗的34例呼吸衰竭患儿及30例正常新生儿,行血气分析、肺泡-动脉血氧分压差(A-aDO2)、呼吸指数(RI)、氧合指数(OI)等氧合功能指标监测,并根据病情分组进行对比观察。结果新生儿呼吸衰竭与正常新生儿比较A-aDO2、OI、RI差异有统计学意义(P<0.001);轻度呼吸衰竭组与重度呼吸衰竭组两组PaO2、A-aDO2、OI、RI差异有统计学意义(P<0.05);呼吸衰竭机械通气时间48 h内撤机组与48 h后撤机组在A-aDO2、OI、RI、PCO2差异有统计学意义(P<0.05)。结论应用氧合功能指标对新生儿呼吸衰竭的早期诊断、判断病情程度及评估预后有重要临床意义。Objective To study the clinical significance of monitoring indexes of oxygen function in the neonate with respiratory failure. Methods 34 neonates with respiratory failure treated with ventilator in neonatal intensive care unit and 30 normal neonates were detected for arterial blood gas to calculate A - aDO2,OI,and Rl,these neonates were divided into groups according to the severity and change of illness. Results There was significantly difference for A - aDO2,OI,and RI in the neonates with respiratory failure and the normal neonates between the two groups （P 〈 0. 01 ） . There was significantly difference for PaO2, A- aDO2,OI,and RI in the neonates with moderate respiratory failure and severe respiratory failure （P 〈0.05）. There was significantly difference for A -aDO2,OI,RI,PCO2 in the neonate treated with ventilator in 48 hours and after 48 hours （P 〈0.05）. Conclusion The clinical evaluation by these indexes of oxygen function for newborn with respiratory failure is beneficial in diagnosing early ,judging the severity of illness, evaluating prognosis.

关 键 词：呼吸衰竭 新生儿 氧合功能指标 

分 类 号：R722.1[医药卫生—儿科]