B型钠尿肽对急性心肌梗死溶栓后再灌注的预测价值  

Prognostic value of B-type natriuretic peptide for assessing myocardial reperfusion after thrombolytic therapy on acute myocardial infarction

作　　者：杜孝奔[1] 刘宁[1] 刘建军[1] 

机构地区：[1]同济大学附属同济医院急诊科,上海200065

出　　处：《中国医药导报》2008年第3期38-40,共3页China Medical Herald

摘　　要：目的:探讨血浆B型钠尿肽(BNP)预测急性心肌梗死(AMI)溶栓治疗后血管再通情况的价值。方法:对112例接受溶栓治疗的AMI患者,同时使用血浆BNP水平和临床间接指征判断血管再通情况,并对它们的结果进行比较。结果:血浆BNP水平对血管未通判断的准确性较临床间接指征高(P=0.000);敏感性和特异性与后者比较,差异无统计学意义(P=0.069,0.051);判断血管再通的敏感性、特异性和准确性低于临床间接指征(P=0.000)。结论:对AMI接受溶栓治疗的患者来说,血浆BNP水平可帮助判断血管未通,从而为病情评估和进一步治疗提供依据。Objective：To evaluate the prognostic value of B-type natriuretie peptide （BNP） for assessing myocardial reperfusion of the patients with acute myocardial infarction（AMI） who received thrombolytic therapy. Methods：The 112 patients with acute myocardial infarction who received thrombolytie therapy were assessed by plasma level of BNP and indirect clinical index simultaneously to diagnose if the obstructive coronary arteriongraphy had reperfusion. And then, their consequence were compared each other.Results：As diagnosing non-reperfusion,correctness of BNP was higher than that of indirect clinical index （P=0.000）, and the sensitivity and specificity were similar with the later （P=0.069, 0.051）. Sensitivity, specificity and correctness of BNP were lower than that of indirect clinical index when diagnosing reperfusion（P=0.000）. Conclusion：Plasma level of BNP can make for diagnosing non-reperfusion after thrombolysising. So it can offer evidence for assessing their condition and further treatment for the patients with AMI.

关 键 词：急性心肌梗死(AMI) 溶栓 B型钠尿肽(BNP) 预测 

分 类 号：R541[医药卫生—心血管疾病]