男女性生殖道支原体感染药敏谱对比分析  

Comparative Analysis of Male and Female on Drug Sensitivity Test and Mycoplasma Infection Condition in Genital Duct

作　　者：黄明孔[1] 季明勇[1] 唐永军[2] 孟衍建[1] 兰君[1] 

机构地区：[1]四川生殖卫生学院附属医院,成都610041 [2]四川生殖卫生学院流行病学教研室,成都610041

出　　处：《中国计划生育学杂志》2008年第1期32-34,共3页Chinese Journal of Family Planning

摘　　要：目的:了解男性和女性生殖道支原体的感染状况,分析男性和女性感染支原体的药物敏感情况,为临床工作提供参考。方法:统计分析门诊675例疑似或需排除非淋菌性尿道炎(NGU)或粘液脓性宫颈炎(MPC)的患者尿道或宫颈分泌物支原体分离、鉴定及药敏检测结果。结果:男性支原体的感染占53.2%(202/380),女性占55.3%(163/295)。在9种抗生素的药物敏感试验中,仅强力霉素在高度、中度敏感和耐药的比例分布上,两性差异有统计学意义(P<0.05)。结论:男女两性支原体的感染率,无论是单一解尿支原体(Uu)感染、单一人型支原体(Mh)感染或是Uu和Mh混合感染,差异均无统计学意义。对交沙霉素、美满霉素、阿奇霉素、司巴沙星、罗红霉素、左氧氟沙星、氧氟沙星、克林霉素等8种抗生素的敏感度,两性差异均无统计学意义。Objective： To understand the mycoplasma infection condition of male and female, and analyze the drug sensitivity and resistance for male and female being infected by mycoplasmal fo provide a reference for the clinical work. Methods： 675 outpatients who were suspected or needed to expel nongonococcal urethritis（NGU） or mucopurulent cervicitis （MPC） were taken the sample from the urethra or cervix to carry out mycoplasma separation, authentication, count and drug sensitivity with the reagent kit. Results ： For the mycoplasma infection rate, the male was 53.2% （ 202/380）, and the female was 55.3% （ 163/295,）： The comparison of infection rates of mycoplasma to the medicine sensitiveness of 9 kinds of antibiotics showed that only doxycycline appeared statistically difference in the high and medium degree of sensitiv!ty and the distribution of resistivity. Conclusion： It appears no statistically significance between the men and women＇s mycoplasma infection rates, including the rates of single ureaplasma urealyticum （Uu） infection, single mycoplasma hominis （Mh） infection or the Uu and Mh mixed infection. It shows no statistically significance in the sensitivity degrees among 8 kinds of antibiotics including josamycin, minocycline, azitromycin, sparfloxacin, roxithromyein, levofloxacin, ofloxacin and clindamycin.

关 键 词：解脲支原体 人型支原体 感染 药敏及耐药性 

分 类 号：R446.5[医药卫生—诊断学]