良性前列腺增生组织对钛宝石激光的吸收和散射特性  

Absorption and Scattering Characteristics of Human Benign Prostatic Hyperplasia Tissue with Ti:Sapphire Laser Irradiation in Vitro

作　　者：魏华江[1] 邢达[1] 何博华[2] 吴荣海[3] 谷怀民[1] 巫国勇[4] 陈雪梅[5] 

机构地区：[1]华南师范大学激光生命科学研究所、暨激光生命科学教育部重点实验室,广东广州510631 [2]广东药学院临床医学系外科,广东广州510224 [3]广东省江门市中心医院泌尿外科,广东广州529071 [4]中山大学第一附属医院心胸外科,广东广州510080 [5]中山大学第一附属医院眼科,广东广州510080

出　　处：《光谱学与光谱分析》2008年第1期10-13,共4页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(60378043;30470494);广东省自然科学基金项目(015012,04010394);广东省科技计划项目(2004B10401011)资助

摘　　要：研究了经尿道等离子体双极电切除术(PKRP)切除和经尿道前列腺电切术(TURP)切除的前列腺增生(BPH)组织对640,660,680,700,720,740,760,780,800,820,840,860和880nm波长的钛宝石激光的光学特性及其差异,实验采用双积分球测量系统以及反向倍增法获取BPH组织的吸收和散射特性参数。结果表明:PKRP和TURP切除的BPH组织对这13个不同波长的激光的吸收系数和约化散射系数都是随着激光波长增大而明显减小的,PKRP切除的BPH组织对这同一波长的激光的吸收系数和约化散射系数都明显较TURP切除的BPH组织对相应的波长的激光的吸收系数和约化散射系数要小,PKRP和TURP切除的BPH组织的吸收系数以及约化散射系数的最大值都在640nm,其值分别为(0.885±0.022)和(0.955±0.024)mm-1以及(1.564±0.039)和(1.658±0.042)mm-1,其差异分别为7.91%以及6.01%,其最小值都在880nm,其值分别为(0.443±0.011)和(0.455±0.011)mm-1以及(1.117±0.028)和(1.197±0.030)mm-1,其差异分别为2.71%以及7.16%。PKRP和TURP切除的BPH组织对660nm的吸收系数的差异最大,其值为8.95%,其差异最小在860nm,其值为1.75%,PKRP和TURP切除的BPH组织对800nm的约化散射系数的差异最大,其值为9.13%,其差异最小在640nm,其值为6.01%。The optical properties and their differences of human benign prostatic hyperplasia （BPH） tissues removed using transurethral plasma kinetic resection of the prostate （PKRP） and transurethral vaporization of the prostate （TUVP） at 640, 660, 680, 700, 720, 740, 760, 780, 800, 820, 840, 860 and 880 nm of Ti： Sapphire laser were studied in vitro. The measurements were performed using a double-integrating-sphere setup, and the absorption and scattering properties were assessed using the inverse adding-doubling method. The results of measurement showed that the absorption coefficients and reduced scattering coefficients of BPH tissues removed using PKRP and TURP obviously decreased with the increase in the wavelength for thirteen different laser wavelengths. The absorption coefficient and reduced scattering coefficient of BPH tissues removed using PKRP at a certain laser wavelength were obviously smaller than that of BPH tissues removed using TUVP at the same laser wavelength. The maximum absorption coefficient and maximum reduced scattering coefficient of BPH tissues removed using PKRP and TURP were respectively （0.885±0.022） and （0.955±0.024）mm^-1, and （1.564±0.039） and （1.658±0.042）mm^-1 at 640 nm, their differences were respectively 7.91% and 6.01%, and the minimum absorption coefficient and minimum reduced scattering coefficient of BPH tissues removed using PKRP and TURP were respectively （0.443±0.011） and （0.455±0.011）mm^-1, and （1.117±0.028） and （1.197±0.030）mm^-1 at 640 nm, their differences were respectively 2.71% and 9.13%. The maximum difference in the absorption coefficients of BPH tissues removed using PKRP and TURP is 8.95% at 660 nm, and the minimum difference is 1.75% at 860 nm. The maximum difference in the reduced scattering coefficients of BPH tissues removed using PKRP and TURP is 9.13% at 800 nm, and the minimum difference is 6.01% at 640 nm.

关 键 词：人良性前列腺增生组织 吸收和散射特性 钛宝石激光 积分球 

分 类 号：R318.5[医药卫生—生物医学工程]