前列腺液白细胞含量与男性不育的相关性分析  

Analysis of the correlation between expressed prostatic secretion leukocyte counts and male infertility.

作　　者：刘雅峰[1] 周灿权[1] 欧建平[1] 李宇彬[1] 邓春华[1] 

机构地区：[1]中山大学附属第一医院生殖医学中心,广州510080

出　　处：《中国优生与遗传杂志》2008年第1期104-105,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨前列腺液白细胞含量与精液主要参数和指标的关系。方法对入选的260例男性不育患者进行前列腺液(EPS)常规检查计数白细胞和解脲支原体培养,按照WHO人类精液实验室手册要求检测精液主要参数、精子形态分析、精子顶体酶活性、精浆抗体(AsAb)等,分析前列腺白细胞与男性不育相关因素的关系。结果260例中炎症组93例(EPS中WBC≥10个/HP):非炎症组(EPS中WBC<10个/HP)167例。炎症组精液的精子密度、精子活动率、a+b级活力精子率、精子顶体酶阳性率均低于非炎症组(P<0.05);而精液液化时间、精子畸形率、精浆抗体(AsAb)、前列腺液解脲支原体阳性率高于非炎症组(P<0.05)。两组的精液量及pH值差异无显著性。结论前列腺液中白细胞含量对精液质量有一定的影响,慢性前列腺炎是导致男性不育的原因之一。Objective：To study the relationship between expressed prostatic secretion（EPS） white blood cells（WBC） counts and semen major parameters.Methods：EPS routine examination and UU detection were carried out;Semen major parameters,abnormal morphological sperm rate,sperm acrosin reaction,and AsAb were measured and analyzed in 260 infertile men according to WHO laboratory handbook about human semen.Results：ESP WBC≥10/HP were 75 cases in 238 male infertility,set up into inflammatory group;ESP WBC〈10/HP were 163 cases,set up into non-inflammatory group.Semen concentration,motility,a＋b grade motility,and sperm acrosin reaction rate in inflammatory group were lower than in non-inflammatory group（P〈0.05）;Longer liquifying time,higher abnormal morphological sperm,ESP UU infection rate and AsAb positive rate were observed in inflammatory（P〈0.05）;Sperm volume and pH value were not significantly different between two groups（P〉0.05）.Conclusion：ESP WBC counts have effect on sperm quality,which can be considered as one of the important reasons resulting in male infertility.

关 键 词：前列腺液白细胞 精液参数 男性不育 

分 类 号：R698.2[医药卫生—泌尿科学]