鸡血藤黄酮类化合物的研究  被引量:48

Five flavonoids from Spatholobus suberectus

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作  者:郑岩[1] 刘桦[1] 白焱晶[1] 马彦梅[1] 赵玉英[1] 

机构地区:[1]北京大学医学部药学院天然药物学系,北京100083

出  处:《中国中药杂志》2008年第2期152-154,共3页China Journal of Chinese Materia Medica

基  金:国家自然科学基金项目(20432030)

摘  要:目的:研究鸡血藤Spatholobus suberectus的化学成分。方法:用色谱法分离,用波谱法鉴定结构。结果:分离并鉴定了5个黄酮类化合物,分别为3-羟基-9-甲氧基紫檀烷(1)、芒柄花素钠(2,7-二羟基-4′-甲氧基异黄酮钠)(2)、芒柄花素(3)、大豆苷元(4)、7,4′-二羟基-3′-甲氧基异黄酮(5)。结论:化合物1,2,5为首次从本属植物中得到。Objective: To investigate the chemical constituents of Spatholobus suberectus. Method: Chromatographic techniques were employed for isolation and purification of the constituents. The structures were elucidated by spectral analysis. Result: Five flavonoids were isolated from S. suberectus and their structures were identified as medicarpin( 3-hydroxy-9-methoxypterocarpane, 1 ), formononetin sodium ( 7-O-sodium -4'-methoxyisoflavone,2), formononetin ( 7 -hydroxy-4'-methoxyisoflavone, 3 ), daidzein ( 7, 4'- dihydroxyisoflavone,4), 7, 4'-dihydroxy-3'-methoxyisoflavone 5). Conclusion: Three compounds 1, 3 ,5 were obtained from the genus for the first time.

关 键 词:鸡血藤 黄酮 

分 类 号:R284[医药卫生—中药学]

 

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