长枝沙菜的化学成分研究  

Chemical constituents of Hypnea charoides

作　　者：廖小建[1] 徐石海[1] 杨剑萍[1] 郭书好[1] 

机构地区：[1]暨南大学化学系,广东广州510632

出　　处：《中草药》2008年第1期7-9,共3页Chinese Traditional and Herbal Drugs

基　　金：国家863基金资助项目(2006AA09Z408);广东省自然科学基金资助项目(39120);广东省科学计划基金资助项目(2004B30101011)

摘　　要：目的对长枝沙菜乙醇提取物的化学成分进行研究。方法用化学和色谱方法进行分离,用IR、MS、NMR等方法鉴定化合物的结构。结果分离得到3个化合物,分别为3,6-二甲基-8-(4-亚甲基-3-庚氧基)-1-辛胺(Ⅰ)、棕榈酸钾(Ⅱ)、(2R,1′S,2′S,3′R)-N-[1′-羟甲基-2′,3′-二羟基十七烷基]-2-羟基-12,13-亚甲基二十四脂肪酰胺(Ⅲ)。结论其中化合物、为新化合物,分别命名为沙菜胺和沙菜酰胺。Objective To investigate the chemical constituents of red algae Hypnea charoides. Methods The constituents were isolated by column chromatography and their structures were elucidated by chemical properties and spectroscopic analyses. Results Three compounds were isolated and their structures were identified as 3, 6-dimethyl-8-（4-methyleneheptan-3-yloxy） octane-l-amine （ Ⅰ ）, palmitate-K （ Ⅱ ）, and （2R, 1＇S, 2＇S, 3＇R）-N-（1＇-hydroxymethyl-2＇, 3＇-dihydroxy-heptadecenyl）-2-hydroxy-12, 13-methylene- tetracosanamide （ Ⅱ ）. Conclusion Compounds Ⅰ and Ⅲ are new compounds named as charoidesine and charoidesamide.

关 键 词：长枝沙菜 红藻 沙菜胺 沙菜酰胺 

分 类 号：R284.1[医药卫生—中药学]