父母支原体感染与新生儿感染关系的研究  

Infection of Ureaplasma Urealyticum between Parents and Their Newborns

作　　者：梅少芬[1] 王蕴慧[1] 

机构地区：[1]中山医科大学孙逸仙纪念医院妇产科

出　　处：《中华妇产科杂志》1997年第5期302-304,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的：探讨父母解脲支原体（ＵＵ）感染与新生儿ＵＵ感染的关系，以及新生儿ＵＵ感染与分娩方式的关系。方法：于１９９５年７～１２月应用聚合酶链反应（ＰＣＲ）技术对１５７例孕妇宫颈管分泌物拭子标本作ＵＵ检测，凡阳性者分别取其丈夫尿道分泌物和新生儿鼻咽部分泌物拭子作ＵＵ检测。结果：孕妇ＵＵ阳性率１７．２％；ＵＵ阳性孕妇之丈夫及其新生儿ＵＵ阳性率分别为６６．７％及５５．６％；其中仅母亲阳性的新生儿ＵＵ阳性２例（２／９），父母ＵＵ均阳性者新生儿ＵＵ阳性率为７２．２％（１３／１８）（Ｐ＜０．０５）。剖宫产与阴道分娩的新生儿ＵＵ阳性率分别为７０．０％及４７．１％，两者间差异无显著性（Ｐ＞０．０５）。结论：父母均存在ＵＵ感染时，其新生儿ＵＵ感染的机会增加；感染途径主要为宫内而不是产道。Objective: To investigate the relationship of ureaplasma urealyticum (UU) infection between parents and their newborns, and the possible influence of the modes of delivery on infants UU infection. Methods: The cervical swab samples were obtained from 157 pregnant women around 32￣36 gestational weeks for the determination of UU by polymerase chain reaction (PCR). In those UU positive cases, swab samples were taken both from the their husbands′urethra and the their newborns′ throat after delivery. Results: UU was detected in 27 pregnant women (17.2%), among which it was positive in 66.7% of their husbands, 55.6% of the neonates. Out of the 9 infected women whose husbands were negative only 2 neonates were positive, while 72.2% (13/18) of the neonates found UU infection when both of their parents were positive ( P <0.05). The positive rate of neonates was 47.1% in the group of vaginal delivery and 70.0% in the cesarean section group ( P >0.05). Conclusion: The neonatal UU infection is strongly associated with UU infection of their parents, and it is mainly an intrauterine infection rather than infection aquired during delivery.

关 键 词：支原体感染 垂直传播 新生儿 

分 类 号：R691.3[医药卫生—泌尿科学]