细菌吸收HLAI类抗体的能力观察  

An Observation on Capacity for Bacteria Absorbing HLA Class I Antibodies

作　　者：刘若英[1] 

机构地区：[1]贵阳医学院临床微生物学和免疫学教研室

出　　处：《贵阳医学院学报》1997年第2期112-115,共4页Journal of Guiyang Medical College

基　　金：卫生部资助

摘　　要：为探讨ＨＬＡＩ类分子和细菌间是否有共同抗原，我们用细胞毒抗体吸收试验进行了观察，实验用１４株细菌，吸收了６个特异性的７份血清。结果表明，所试细菌均有一定的吸收能力，菌细胞明显强于培养上清液，但缺乏严格的特异性。同一细胞同时进行的吸收和封闭试验表明，细菌吸收抗体的能力和对淋巴细胞表面抗原的封闭作用是相关的。本研究提示ＨＬＡＩ类分子和细菌间确有共同抗原存在。In order to explore the common antigens between HLA class I molecules and bacteria, absorptive tests were carried out with 14 strains of bacteria and 7 antisera of 6 specificities The results showed:all bacterial strains were able to absorb some HLA class I antibodies, and bactreial cells were significantly much powerful than culture supernatants There was no strict specificity in bacteria or antisera A numbe of absorbing and blocking tests were carried out simultaeneously and the results shoued: absorbing was associated with blocking It seems that there are some similar determinants between HLA class I molecules and bacteria

关 键 词：细菌 人白细胞抗原 细胞毒抗体吸收 

分 类 号：R392.11[医药卫生—免疫学] R37[医药卫生—基础医学]