荧光分子成像技术概述及研究进展  

Introduction of Fluorescence Molecular Imaging Technology and its Development

作　　者：朱新建[1] 宋小磊[1] 汪待发[1] 白净[1] 

机构地区：[1]清华大学生物医学工程系

出　　处：《中国医疗器械杂志》2008年第1期1-5,25,共6页Chinese Journal of Medical Instrumentation

基　　金：国家自然科学基金(30670577;60571013;60331010);清华-裕元基金973(2006CB705700);博士点基金

摘　　要：荧光分子成像技术以低成本、简单易行、对生物体无电离辐射等优势在活体中进行疾病观察、药物及生物学等研究中发挥越来越重要的作用。对荧光分子成像技术中几个重要的部分,包括荧光分子探针、成像系统、重建算法等方面的内容和进展做了简要的描述,并介绍了荧光分子成像技术的应用和发展趋势。In vivo fluorescence molecular imaging plays a more and more important role in the observation of diseases, drug research and biology research because of its low cost, simplicity and no ionizing radiation to biological tissue. Herein, the most important parts of the optical fluorescence molecular imaging and their advances are summarized, including fluorescent molecular probes, imaging systems and reconstruction algorithms. The application and development trend of this technology are also introduced in this paper.

关 键 词：荧光分子成像 成像系统 重建 

分 类 号：R318[医药卫生—生物医学工程]