冷习服及其冻伤对大鼠循环血中血管内皮细胞计数的影响  

EFFECTS OF COLD ACCLIMATION AND FROSTBITE ON THE COUNTS OF CIRCULATING ENDOTHELIAL CELL IN RATS

作　　者：颜培华[1] 李凤芝[1] 杨增仁[1] 刘嘉瀛[1] 刘友梅[1] 孙方人[1] 

机构地区：[1]军事医学科学院卫生学环境医学研究所

出　　处：《解放军预防医学杂志》1997年第4期254-256,共3页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：测定了冷习服及未习服雄性Ｗｉｓｔａｒ大鼠冻伤前后血中血管内皮细胞数。结果表明，冷习服（２～６℃，４周）可使大鼠循环血中血管内皮细胞（ＣＥＣ）数非常显著地高于正常大鼠（２０±２℃），冻伤前后冷习服冻伤组ＣＥＣ无明显差别；未冷习服大鼠冻伤后ＣＥＣ非常明显的增加；冻后４ｈ冷习服冻伤组ＣＥＣ数明显低于未冷习服冻伤组。结果提示，冷习服后大鼠血管内皮细胞代谢旺盛、更新加速，且其抗冷损伤的能力增加。The circulating endothelial cell(CEC) counts were determined in cold acclimated(CA) and unacclimated(UA) male Wistar rats before and after freezing injury of right hind feet. Cold acclimation(2-6℃,4 wk)induced an increased CEC count than unacclimated group (20±2℃),P<0.01.After freezing injury, CEC counts of CA group remained vertually unchanged, while those of UA group grew up definitely and a significant higher level of CEC than CA group was found at 4h post-freezing. These results suggested that the metabolism and ability to resist cold injury of vascular endothelial cells were enhanced by cold acclimation.

关 键 词：冻伤 冷习服 内皮细胞 计数 

分 类 号：R645.02[医药卫生—外科学]