利喜定用于预防全麻诱导插管期反应的探讨  

CLINICAL OBSERVATION OF LIXIDING TREATMENT FOR CARDIOVASCULAR RESPONSE INDUCED BY ENDOTRACHEAL INTUBATION

作　　者：刘良田[1] 杜雪江[1] 孟兴凯[2] 

机构地区：[1]内蒙古医学院附属医院麻醉科,内蒙古呼和浩特010050 [2]内蒙古医学院附属医院外科,内蒙古呼和浩特010050

出　　处：《内蒙古医学院学报》2007年第6期397-399,共3页Acta Academiae Medicinae Neimongol

基　　金：内蒙古医学院重大科研基金资助项目(2003ZD001)

摘　　要：目的：评价利喜定预防气管内插管致心血管反应的临床效果及安全性。方珐：将64例上腹部手术病人随机均分为2组：单纯全麻组（A组）及静脉注射利喜定0．5mg／kg组（B组）。观察两组全麻诱导后及插管后1～10min心率、收缩压、舒张压和平均动脉压变化。结果：利喜定组病人插管后血压和心率与插管前相比，变化不明显（P〉0．05）；与同期对照组相比，变化显著（P〈0．05）。结论：利喜定能够有效预防气管插管致心血管反应，降低围插管期心血管并发症发生率。Objective：To evaluate the clinical effects of lixiding treatment for cardiovascular response induced by endotracheal intubation. Methods： 64 patients were randomly divided into two groups： single anesthesia （A group ） and lixiding （B group ）, receiving lixiding at a dose of 0.5mg/kg. Heart rate, systolic and diastolic pressure, and mean arterial pressures（MAP） were measured following the induction and 1 to 10 minutes following the intubation. Results： MAP and HR of the patients in B group had no significantly increased after administration of lixiding; and there was significant difference comparing with that in A group. Conclusion： Lixiding is effective and safe for preventing the cardiovascular response to endotracheal intubation.

关 键 词：利喜定(乌拉地尔) 全麻 气管内插管 

分 类 号：R971.2[医药卫生—药品]