三种不同产地天麻乙酸乙酯提取物对兔血小板聚集作用的影响  

Effect on the Platelet Aggregation in Rabbit of the Gastrodia Elata Blume. Extractive from Different Regions

作　　者：田野[1] 李松梅[1] 李秀芳[1] 陈顺芳 林青[1] 

机构地区：[1]云南中医学院,云南昆明650200 [2]昭通市天麻研究所,云南昭通657300

出　　处：《云南中医学院学报》2008年第1期31-33,共3页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(NO:30760305)

摘　　要：目的:对不同产地天麻进行血小板聚集作用的试验研究,对比天麻药材因产地差异对药效产生的影响。方法:采用二磷酸腺苷(ADP)诱导血小板聚集法研究不同产地天麻药效学差异。结果:云南昭通、湖北、陕西天麻提取物乙酸乙酯部分均能抑制由二磷酸腺苷(ADP)诱导的家兔血小板聚集功能。云南昭通天麻提取物乙酸乙酯部分的作用明显强于其他产地。结论:天麻乙酸乙酯提取物具有显著的抗血小板聚集作用,且以云南昭通天麻作用最强。Objective：To study the platelet aggregation effect of Gastrodia elata Blume. from different areas, comparing the pharmacodynamic action contrast of Gastrodia elata Blume. from different areas. Method： ADP inducing platelet aggregation method was used to study the pharmacodynamic action contrast of Gastrodia elata Blume. from different areas. Results： Gastrodia elata Blume. EtOAc extractive from Yunnan, Hubei, Shanxi can inhibit the platelet aggregation of ADP inducing in rabbit. Conclusion ： Gastrodia elata Blume. EtOAc extractive from that three different areas can conspicuously inhibit the platelet aggregation and Gastrodia elata Blume. EtOAc extractive of Yunnan has the best effect.

关 键 词：天麻 血小板聚集 乙酸乙酯提取物 

分 类 号：R285.5[医药卫生—中药学]