蘑菇伞封堵器治疗动脉导管未闭的疗效与安全性观察  

CLINICAL STUDY OF TRANSCATHETER CLOSURE OF PATENT DUCTUS ARTERIOSUS WITH OCCLUDER DEVICE

作　　者：彭永权[1] 李刚[1] 黄维义[1] 范忠才[1] 石娟[1] 李家富[1] 

机构地区：[1]泸州医学院附属医院心内科,四川泸州646000

出　　处：《泸州医学院学报》2008年第1期53-55,共3页Journal of Luzhou Medical College

摘　　要：目的:观察蘑菇伞封堵器治疗动脉导管未闭(PDA)的临床疗效与安全性。方法:25例单纯PDA患者采用蘑菇伞动脉导管封堵器经皮经股静脉封堵冶疗PDA,应用X线造影术观察即刻疗效,术后72h、1个月、3个月分别行超声心动图评价治疗效果。结果:X线降主动脉造影测量PDA最窄处的直径平均5.9±1.2(1.5～11)mm,封堵器直径平均11.8±1.5(6～16)mm。全组技术成功率100%;术后10分钟降主动脉造影显示25例均无残余分流。术后肺动脉平均压较术前明显下降(P<0.05)。术中无任何严重并发症,3个月随访,未发现残余分流、封堵器移位、溶血、血栓或主、肺动脉狭窄。结论:应用蘑菇伞动脉导管封堵器经导管介入治疗PDA安全有效,创伤小,成功率高,操作简单。Objective：To evaluate the efficiency of transcatheter closure of patent ductus arteriosus（PDA）using occluder device.Methods：25 patients with PDA were treated with transcatheter closure with duct occluder device. Each PDA was occluded through the percutaneous procedure.Aortographies were made to evaluate the efficiency immediately after the procedure.Echocardiographies were performed 72 hours,1 month and 3 months after the closure to find whether there was residual shunt or recanalization.Results：The smallest diameter of PDA measured by aortography was 5.9±1.2 （1.5-11）mm,and the mean diameter of duct occluder device measured by aortography was 11.8±1.5 （6-16）mm.The technical successful rate was 100%. Aortography showed that 25 patients had been completely closed 10 minutes after operation, the mean pressure of pulmonary artery declined significantly after operation （P〈0.05）.No complications happened during operation.Residual shunt,the place of duct occluder device, hemolysis,embolism and aortic stenosis didn＇t happen during 3 months follow-up.Conclusion ：Transcatheter closure of PDA using duct occluder device is safe and efficient.The successful rate is high, and there is less trauma.

关 键 词：动脉导管未闭 介入治疗 封堵器 

分 类 号：R541.1[医药卫生—心血管疾病]