卵巢恶性肿瘤患者血清CA72-4和SIL-2R水平的检测及其临床意义  

Clinical Significance of Serum CA72-4 and SIL-2R Detection in Patients with Malignant Ovarian Neoplasm

作　　者：高劲松[1] 李建明[1] 李桂珍[2] 张浩[3] 

机构地区：[1]长沙医学院,长沙410219 [2]武汉市第一医院,武汉430022 [3]武汉市中心医院,武汉430025

出　　处：《现代生物医学进展》2008年第2期307-308,共2页Progress in Modern Biomedicine

摘　　要：目的:探讨良、恶性卵巢肿瘤患者血清中SIL-2R和卵巢癌相关抗原CA72-4的临床应用价值。方法:采用酶联免疫吸附测定法检测正常对照组,卵巢肿瘤良、恶性患者组的血清CA72-4及SIL-2R的值,观测其在恶性卵巢肿瘤诊断中的敏感性。结果:在恶性卵巢肿瘤患者中,CA72-4及SIL-2R的值均显著高于良性卵巢肿瘤组及正常对照组,两者联合检测恶性卵巢肿瘤的敏感性为83.3%。结论:血清CA72-4及SIL-2R的联合检测在恶性卵巢肿瘤的诊断及预后判断方面有较好的临床应用价值。Objective： To investigate the clinical significance of serum tumor markers CA72-4 and SIL-2R in patients with ovarian neoplasm. Methods： The level of serum or plasma CA72-4 and SIL-2R in patient with benign, malignant ovarian neoplasm and normal control group was detected by enzyme-linked immunosorbent assay and their sensitivity in diagnosing malignant ovarian neoplasm was investigated. Results： The level of serum or plasma CA72-4 and SIL-2R in patient with malignant ovarian neoplasm was significantlY higher than that of patient with benign ovarian neoplasm and normal control group, The sensitivity of combined examination with CA72-4 and SIL-2R had reached 83.3% in diagnosing malignant ovarian neoplasm. Conclusion： Combined examination with serum CA72-4 and SIL-2R has important clinical significance in diagnosing malignant ovarian neoplasm and prognosis decision.

关 键 词：CA72—4抗原 SIL-2R 卵巢恶性肿瘤 

分 类 号：R392.11[医药卫生—免疫学]