美罗培南临床应用2732例的疗效评价  

Efficaly of Meropenem Against Infections:A Clinical Evaluation of 2732 Cases

作　　者：刘长庭[1] 王增武 

机构地区：[1]解放军总医院南楼呼吸科,北京100853 [2]阜外医院外科,北京100037

出　　处：《中华医院感染学杂志》2008年第2期249-250,共2页Chinese Journal of Nosocomiology

摘　　要：目的分析美罗培南临床应用的疗效和细菌清除率。方法对国内170余所医院应用美罗培南治疗各种感染的2732例资料进行分析整理。结果美罗培南对血液病并发各种感染、肺部感染、肝胆胰系统感染、移植患者并发感染的临床有效率分别为80.3%、87.1%、63.6%、73.3%;临床总有效率为83.5%;美罗培南对血液病并发感染、肺部感染、肝胆胰感染、移植患者并发感染细菌清除率分别为33.5%、66.2%、65.5%、66.7%;总细菌清除率为52.7%。结论美罗培南在临床治疗各种感染中效果好,总有效率为83.5%;细菌清除率为52.7%。OBJECTIVE To analyze the curative effect and bacterial clearance of meropenemagaint infections. METHODS To analyze 2732 cases with infection from more than 170 hospitals after meropenem. RESULTS The effectiveness ratio on various infections of blood, lungs treatmeot liver, gallbladder, and pancreas systems and on infections after transplantabions was 80. 3%, 87. 1%, 63. 6% and 73.3%, respectively; the total clinical effectiveness ratio was 83. 5%. The bacterial clearance ratio in various infections of blood, lungs liver, gallbladder, and pancreas systems and in infections after transplantations was 33.5%, 66. 2%, 65. 5% and 66.7%, respectively; the total bacterial clearance ratio was 52. 7%. CONCLUSIONS Meropenem is effective against infection in clinical patients. The total clinical effectiveness ratio is 83.5%. The total bacterial clearance ratio is 52. 7%.

关 键 词：美罗培南 临床 疗效 细菌清除 

分 类 号：R978.1[医药卫生—药品]