极化液个体化治疗对外科高血糖患者出院后的影响调查  

Effect of Individualized Treatment with GIK Polarized Solution on Discharged Surgical Patients with Hyperglycaemia

作　　者：于永洲[1] 王占科[1] 潘小清[1] 

机构地区：[1]解放军第94医院,南昌市330002

出　　处：《中国药房》2008年第5期390-392,共3页China Pharmacy

基　　金：江西省卫生厅资助课题(20052044);南京军区医药卫生"十一五"资助重大课题(06Z25)

摘　　要：目的:分析极化液个体化治疗对外科高血糖患者出院后的影响。方法:采用问卷填写方式,对我院2287例(包括入院前已存在糖尿病者125例)接受静脉极化液个体化治疗出院1a后的外科高血糖患者的极化液不良反应情况进行调查。结果:所有被调查者无1例继发糖尿病、高血压、低血糖症或对胰岛素产生心理依赖感;0.6%的被调查者担心日后仍会出现后遗症;在入院前即存在糖尿病且出院后正在使用胰岛素的患者中,有98.5%认为胰岛素能明显减轻糖尿病病情;在入院前即存在糖尿病或高血压且出院后未接受胰岛素治疗的患者中,100.0%认为外科住院期间大剂量使用胰岛素对糖尿病病情或高血压无影响;接受极化液补充营养、控制高血糖、抗炎、保护胰岛B细胞功能的患者分别占99.3%、96.9%、38.3%、5.5%。结论:极化液个体化治疗外科高血糖安全性高,不会出现后遗症。少数患者对极化液怀有恐惧心理,提示医护人员有必要加强对极化液使用的宣传工作。OBJECTIVE： To evaluate the effects of the individualized treatment with GIK（Glucose- insulin - potassium） polarized solution on the discharged surgical patients with hyperglycemia.METHODS： 2 287 surgical patients with hyperglycemia（including 125 who had diabetes before hospitalization） receiving individualized treatment with GIK（Glucose- insulin- potassium） polarized solution and who had been discharged from hospital for 1 year were surveyed by questionnaire to collect the data of adverse drug reactions of the polarized solution.RESULTS： None of the patients had secondary diabetes mellitus, hypertension, hypoglycemia or psychological dependence on insulin; 0.6 % worried about the sequela of GIP ; 98.5 % of the patients who had diabetes prior to hospitalization and have been taking insulin after been discharged from hospital agreed that the symptom of their diabetes was greatly lessened by insulin; 100.0% of the patients who had diabetes prior to hospitalization and received no insulin after been discharged from hospital agreed that taking large dose of insulin during hospitalization had no effect on the symptom of their diabetes or hypertension;99.3% of patients received supplemental nutrition of polarized solution; 96.9 % given hyperglycemia control ; 38.3 % received antiinflammation therapy, 5.5 % received protective therapy for cell function.CONCLUSION： Individual treatment with GIK on the surgical glycemia patients is a safe remedy without sequela.But a few of surgical glycemia patients are afraid of the ADR of the polarized solution, suggesting the importance of publicizing the use of GIK.

关 键 词：极化液 胰岛素 个体化 副作用 

分 类 号：R969.3[医药卫生—药理学]