高空缺氧条件下DPH对脑铁、锌及MDA含量的影响  

Effect of DPH on the Content of Fe, Zn and MDA in Brain under High-altitude Condition

作　　者：梅丹[1] 朱志国[1] 董辉[1] 徐斌[1] 罗卫国[1] 罗军[1] 

机构地区：[1]空军医学高等专科学校,吉林132013

出　　处：《广东微量元素科学》1997年第8期17-19,共3页Trace Elements Science

摘　　要：用原子吸收法测定了高空缺氧条件下DPH对大鼠脑组织铁、锌含量的影响．并测定了脑MDA含量。结果显示：对照组在高空缺氧条件下．脑组织铁含量明显高于用药组P＜0．05）．而脑锌含量明显低于用药组（P＜0．05）。脑组织MDA含量明显高于地面对照组及用药组（P＜0.01）。这表明，在高空缺氧条件下，对照组脑组织过氧化反应增强，高于用药组；脑组织MDA含量与锌含量成反比。The content of Fe and Zn in brain of rats with or without DPH in 7. 5 km high-altitudedetermined by atondc absorption spectrometry. The content of the brain MDA was also observed. The results showed that the content of brain FE in rat without DPH under hith-alti-tude was much higher than that of normal rat and the content of brain Zn of rat with DPHwas much higher than that of rat without DPH under high-altitude. The content of rat brainMDA without DPH was much higher than that of rat with DPH under high-altitude. The oxgen deficiency makes brain metabolism and hydroperoxidate reaction increased while.DPHmakes brain metabolism and hydroperoxidate reaction decreased.

关 键 词：苯妥英钠 高空缺氧 脑组织 丙二醛 铁 锌 

分 类 号：R594.3[医药卫生—内科学]