邻苯三酚自氧化反应的动力学研究  

Kinetics and Mechanism of Pyrogallol Autoxidation

作　　者：袁倬斌[1] 高若梅[1] 

机构地区：[1]中国科学技术大学研究生院,北京100039

出　　处：《高等学校化学学报》1997年第9期1438-1441,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金;中国科学院长春应用化学研究所电分析化学开放实验室基金

摘　　要：利用单扫示波极谱法（并辅以紫外-可见光谱法）研究了邻苯三酚在pH7．20～9．10的Tris－HCl缓冲体系中自氧化反应的动力学．结果表明，在过量溶解O2存在时，反应对邻苯三酚为一级．在一定pH范围内，准一级反应表现速率常数Kapp随pH值的增加而增加，说明H2PYR-比H3PYR对溶解O2具有更高的反应活性．探讨了邻苯三酚自氧化生成半醒自由基和活性氧的反应机理，用速率方程解释了实验现象．并为酶活力测定和药物抗氧活性研究提供了一种新方法．The kinetics of pyrogallol autooxidation has been studied by single-sweeposcillopolarography in Tris-HCI buffer soluton in the PH range 7. 20~9. 10. The reaction wasfirst order to pyrogallol in the presence of excess dissolved O2. The focus was put onpyrogallol autooxidation with products of semiquinone free radical and active oxygen. Amechanism was presented which explains the increase in rate with increasing PH by postulating thatH2PYR-has a greater reactivity with dissolved O2 than H3PYR. The derived rate law is ingood agreement with the experimental observations. The paper also presented a new assayfor superoxlde dismutase and antioxidant activity of pharmaceuticals.

关 键 词：邻苯三酚 自氧化 单扫示波极谱法 动力学 SOD 

分 类 号：O625.312[理学—有机化学]