老年人不稳定心绞痛肌钙蛋白T和CK-MB检测的临床评价  

The clinical evaluation of examining serum troponin T and creatine kase-isoenzyme MB in patients with angina pectoris

作　　者：马莉[1] 

机构地区：[1]山东中医药大学第二附属医院干部保健科,济南250001

出　　处：《中国实用医药》2008年第3期26-27,共2页China Practical Medicine

摘　　要：目的观察不稳定心绞痛患者血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)含量的变化,并评价其对患者预后的临床价值。方法对45例不稳定型心绞痛患者(UAP)、40例稳定型心绞痛患者(SAP)及28例健康成年人分别进行血清cTnT、CK-MB测定,并分析其与心脏事件的关系。结果三组中UAP患者的cTnT浓度显著高于SAP患者及健康成年人(P<0.01),但三组间CK-MB浓度差异无统计学意义(P>0.05);UAP患者中cTnT≥0.1μg/L占48.9%,其中30d内45.5%发生了心脏事件,cTnT<0.1μg/L中8.7%发生心脏事件(P<0.05)。结论cTnT定量检测对判断UAP患者短期内发生心脏事件有较好的预测价值。Objective To evaluate the value of examining serum cardiac troponin T （cTnT） and creatine kase-isoenzyme MB （CK-MB） in patients with angina pectoris. Methods The level of CK-MB, cTnT in the sera was tested among 45 patients with UAP （ Group UAP） ,40 patients with stable angina pectoris （SAP） （ Group SAP） and control group. And the relationships between the changes of cTnT and the cardiac events were analysed. Results The levels of cTnT in group UAP were higher than that in group SAP and control（P 〈 0.01） , but the levels of CK-MB was not different among 3 groups. The incidence of cardiac events within 30 days were significantly higher in group with increased cTnT（ ≥0. 1 μg/L） than that with normal cTnT（ 〈 0. 1 μg/L） （ 48.9% vs 8.7% , P 〈 0. 05）. Conclusion The present study suggested that serum cTnT level show better predictive value for short-term cardiac events in patients with unstable angina pectoris.

关 键 词：不稳定型心绞痛 肌钙蛋白T 预后 老年人 肌酸激酶同工酶 临床价值 

分 类 号：R541.4[医药卫生—心血管疾病]