聚乳酸／聚乙烯醇共混膜的亲水性与降解性能研究  

Study on Hydrophilicity and Degradability of Polyvinyl Alcohol/polylactic Acid Blend Film

作　　者：王华林[1] 盛敏刚[2] 翟林峰[1] 李延红[1] 

机构地区：[1]合肥工业大学化工学院,农产品生物化工教育部重点实验室,合肥230009 [2]池州师范专科学校化学系,池州247000

出　　处：《生物医学工程学杂志》2008年第1期139-142,共4页Journal of Biomedical Engineering

基　　金：安徽省自然科学基金资助项目(01044803)

摘　　要：采用流延法和溶剂蒸发技术,以聚乳酸(PLA)和聚乙烯醇(PVA)为原料,制备可降解PLA/PVA共混膜。研究PLA/PVA共混膜的吸湿、吸水性能及水降解性能,探索共混膜的水降解机制。结果表明,共混膜的吸湿率与吸水率随共混膜中PLA含量的增加而降低;共混膜在生理盐水中的降解过程是分步进行的,降解初期,PLA降解起主导作用,降解后期,PVA降解起主导作用。在PLA降解过程中,溶液的酸性具有催化降解效果,且PLA降解是从非晶区到晶区;PVA的引入,增加了共混膜的亲水性,并对PLA的结晶性能造成一定的破坏,加速PLA降解过程。因此,可通过调整PLA与PVA配比,在一定范围内对PLA/PVA共混膜的亲水性能与降解性能进行调控。Based on casting and solvent evaporation method, the degradable PLA/PVA blend film was prepared with polylactic acid （PLA） and polyvinyl alcohol （PVA） as raw material. The moisture absorbability, water absorbability and degradability of the polylaetie aeid/polyvinyl alcohol （PLA/PVA）blend film were studied; also the degradation mechanism of blend film was investigated. The results showed that the moisture absorption and water absorption of blend film decreased as the concentration of PLA increased. The degradation process of blend film in the normal saline is conducted by stepwise. At the forepart, the degradation of PLA played an important role, while PVA was the main degradation substance later. The solvent acidity could catalyze the degradation of PLA, and degradation of PLA was always turning from noncrystalline region to crystalline region. PVA had abilities to accelerate the degradation of PLA by increasing the hydrophilieity of the blend film and by breaking the erystallinity of PLA. Therefore, the hydrophilieity and degradability of PLA/PVA blend film can be controlled in a certain range by adjusting the proportion of PLA and PVA.

关 键 词：PLA/PVA共混膜 吸湿、吸水性能 降解性能 降解机制 

分 类 号：R318.08[医药卫生—生物医学工程]