8毫米波辐照鼠皮肤损伤观察及温升仿真  

OBSERVATION ON MICE'S SKIN INJURY IRRADIATED BY 8 MILLIMETER WAVE AND TEMPERATURE INCREASE EMULATION

作　　者：张杰[1] 韩黎军[1] 谢涛嵘[1] 齐红星[1] 陈树德[1] 乔登江[1] 

机构地区：[1]华东师范大学物理系光谱学与波谱学教育部重点实验室,上海200062

出　　处：《红外与毫米波学报》2008年第1期56-59,共4页Journal of Infrared and Millimeter Waves

基　　金：国家863计划项目资助项目;上海市科技攻关项目资助(05DZ12031)

摘　　要：采用苏木精-伊红(HE)染色法对8毫米波辐照不同时间的小鼠皮肤组织切片染色.结果表明随着辐照时间的增加,组织损伤也在逐步加深.建立了考虑血流灌注和水分蒸发失热的一维生物热传导模型,数值计算得出动物表皮温升,计算结果与实验测定结果吻合较好.进一步计算得到了不同辐照时间,动物皮肤不同深度的温升.理论计算和实验相结合,得到了温度与组织损伤之间的关系,结果表明当组织温度上升约16℃时,可以引起组织形态的明显变化.The mice skintissue irradiated by 8 millimeter wave for different time was sectioned by histotome. Then they were stained by using Hematoxylin-Eosin （HE） method. The tissues injury was visually exhibited with HE stain method. It was discovered that the scathed part was deeper when the irradiating duration was longer. Then a one-dimension model of skin tissue considering the blood flow and water evaporation rate was built up for emulating the increase of temperature. The emulated temperature increase of the surface was fitted with the experiments. Furthermore, temperature increase of different depth under skin＇s surface was calculated. The results show that the tissue will be destroyed when the temperature increases 16℃.

关 键 词：8毫米波辐照 皮肤损伤 温升仿真 苏木精-伊红染色 

分 类 号：Q6-3[生物学—生物物理学]