离子表面活性剂胶团对阿斯匹林碱水解反应的影响  

Inhibition of Basic Hydrolysis Reaction of Aspirin by Micelles of Ionic Surfactants

作　　者：史振民[1] 刘生昆[1] 张祝莲[1] 巩育军[1] 

机构地区：[1]延安大学化学系

出　　处：《应用化学》1997年第1期110-112,共3页Chinese Journal of Applied Chemistry

摘　　要：离子表面活性剂胶团对阿斯匹林碱水解反应的影响史振民＊刘生昆张祝莲巩育军（延安大学化学系延安７１６０００）关键词表面活性剂，阿斯匹林，碱水解反应，胶团，抑制作用１９９６－０５－０４收稿，１９９６－０８－１２修回阿斯匹林（ＡＳＰ），学名为乙酰水杨酸，有较...Cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS) were used as surfactants and effects of micelles on the basic hydrolysis of aspirin (ASP) were studied spectrophotometrically. When the concentrations of CTAB are larger than 7 3×10 -3 mol/L, there is an inhibition of basic hydrolysis of ASP, the best concentration being 3 25×10 -3 mol/L. At a constant concentration of CTAB, the addition of a small amount of SDS causes the inhibition of CTAB to decrease, indicating that SDS takes part together with CTAB in the formation of mixed micelles.

关 键 词：表面活性剂 阿斯匹林 碱 水解反应 胶团 

分 类 号：R971.1[医药卫生—药品]