AcMNPV核衣壳的形态发生  

MORPHOGENESIS OF AcMNPV NUCLEOCAPSID

作　　者：陈建国[1] 滕俊琳[1] 翟中和[1] 

机构地区：[1]北京大学生命科学学院,北京1008741

出　　处：《微生物学报》1997年第2期83-86,共4页Acta Microbiologica Sinica

基　　金：国家杰出青年科学基金资助课题

摘　　要：报道了缺失多角体蛋白基因的AcMNPV在sf9细胞内核衣壳的形态发生过程。病毒衣壳蛋白首先装配成许多呈束状排列的直径为34nm中空长管状结构,然后是病毒DNA进入管内,装有DNA的长管按一定的长度间隔断开,形成成束的核衣壳,每个核衣壳的大小约34×260nm,最后成束的核衣壳被囊膜包被形成完整的多粒包埋型病毒粒子。In this paper we reported that the nucleocapsid morphogenetic process of AcMNPV in which polyhedrin gene was deleted in the nuclei of sf9 cells. First, the capsid proteins entered the nuclei and assembled many 34 nm diameter long fascicularly arranged hollow-tube structures. Then viral DNA entered these tubes that turned into solid structure with high electronic density. The solid structure separated at a certain distance to form 34×26 rim fascicular bacilliform structure known as nucleocapsid. Finally, fascicular nucleocapsids were wrapped by envelope and became complete multicapsid morphotype viron.

关 键 词：杆状病毒 昆虫病毒 核衣壳 形态发生 

分 类 号：Q939.404[生物学—微生物学] Q965.8