阴离子交换色谱柱保留特性的变化规律及应对措施  

The Changing Rules of the Retention Characteristics of Anion Exchange Column and Counter Measures

作　　者：陈利根[1] 周静红[2] 孙伟振[2] 林群芳[1] 朱孟钦 

机构地区：[1]华东理工大学材料科学与工程学院,上海200237 [2]华东理工大学化学工程联合国家重点实验室,上海200237

出　　处：《分析测试学报》2008年第2期203-205,共3页Journal of Instrumental Analysis

摘　　要：选择对二甲苯氧化体系的高效液相色谱分析为研究对象,详细考察了阴离子交换色谱柱保留特性的变化,在整个色谱柱寿命期间(进样超过1000次),全程采集了保留时间、分离度等数据。在此基础上,得出色谱柱保留特性的变化规律,并提出了相应的应对措施,把整个色谱柱寿命分成3个阶段,分别采用不同条件的流动相。Focusing on the HPLC analysis of the oxidation system of p-xylene, this research has investigated the changes of retention characteristics of anion exchange columns by analysis data such as retention time, resolution through the whole lifecycle of anion exchange column（ injecting times are over 1 000）. The changing rules of anion exchange column were summarised and the counter measures were proposed. The whole lifecycle were divided as three periods and different mobile phase was used.

关 键 词：阴离子交换色谱柱 保留特性 高效液相色谱法 对二甲苯 

分 类 号：O657.72[理学—分析化学]