口服帕罗西汀结合行为疗法治疗早泄的临床研究  

Clinical study on treatment of premature ejaculation with Paroxetine and behavior-therapy

作　　者：邵欣胤[1] 李金彪[1] 

机构地区：[1]山东省莱芜市计划生育指导中心,莱芜271100

出　　处：《中国男科学杂志》2008年第1期18-20,共3页Chinese Journal of Andrology

基　　金：莱芜市2006年度科技计划项目(2006第25-1号)

摘　　要：目的评价低剂量帕罗西汀结合改进的行为疗法治疗早泄的可行性与疗效。方法将120例早泄患者随机分为3组,每组40例。试验组:口服帕罗西汀10mg/次,每晚1次,连服4周,同时进行改进后的行为疗法,为期8周;对照组Ⅰ:口服帕罗西汀20mg/次,每晚1次,连服8周;对照组Ⅱ:行为疗法,为期8周。观察各组治疗后CIPE-5积分变化、有效率、药物副反应。结果试验组治疗后CIPE-5积分及有效率均优于两对照组。药物副反应发生率明显低于对照组Ⅰ(P<0.01)。结论本组联合治疗早泄的方法临床疗效较好,副反应小,预期效果满意,值得推荐。Objective To assess the feasibility and effects of Paroxetine and modified behavior-therapy for treatment of premature ejaculation （PE）. Methods 120 male outpatients with PE were divided randomly into three equal groups.The experiment group was given oral Paroxetine 10mg/day for 4 weeks and modified behavior-therapy for 8 weeks.The control group Ⅰ was given oral Paroxetine 20mg/day for 8 weeks and the control group Ⅱ was given behavior-therapy for 8 weeks. Results After treatment the score of CIPE-5 （Chinese index of sexual function for premature ejaculation） and the successful rate in the experiment group increased than those of two control groups. The side effects of Paroxetine in the experiment group were obviously lower than those of control group Ⅰ （P〈0.01）. Conclusion Lower does of Paroxetine and modified behaviortherapy are safe, efficacious and convenient method for PE.

关 键 词：帕罗西汀 行为疗法 早泄 

分 类 号：R698[医药卫生—泌尿科学]