兔冬眠及梗死心肌的延迟增强磁共振--病理对照研究  

Delayed Enhanced MRI-pathologic Correlation of Hibernation and Infarction Myocardium in Rabbit

作　　者：李铭 赵江民[2] 赵泽华 倪炯 邵志红[2] 王伟忠 

机构地区：[1]上海市中医药大学附属普陀医院放射科 [2]上海市同济大学附属同济医院放射科

出　　处：《中国医学计算机成像杂志》2008年第1期69-73,共5页Chinese Computed Medical Imaging

基　　金：上海市科学技术委员会基金资助编号:034119931;上海中医药大学附属普陀医院青年医学人才培养计划资助项目编号:2007R104A;上海市科学技术委员会“登山行动计划”重点项目编号:064119505

摘　　要：目的:探讨冬眠心肌及梗死心肌的延迟增强磁共振表现。材料和方法:建立兔冬眠及梗死心肌模型,利用1.5T磁共振成像仪对兔冬眠心肌组、梗死心肌组及正常对照组模型进行延迟增强磁共振扫描,分析各组的延迟增强磁共振表现,并与病理结果对照。结果:读片观察仅梗死心肌组可见延迟强化,MRI机器测量结果显示梗死心肌组及冬眠心肌组均较正常心肌延迟增强信号明显升高,但梗死心肌组较冬眠心肌组延迟强化更加明显。结论:梗死心肌及冬眠心肌延迟增强磁共振扫描均有延迟强化,但程度上有显著性差异,可资鉴别;定量测量延迟增强信号可帮助判断这种差异。Purpose： To investigate the MRI manifestations of hibernating myocardium and infarcted myocardium. Materials and Methods： Establish rabbit hibernating myocardium and infarcted myocardium model, all rabbits performed delay - enhanced MRI （DE - MRI） three days after surgery. The appearances of DE - MRI were compared with the results of pathological results, and were analyzed the appearances of DE - MRI comparatively. Results： Hyper - enhancement of focus segments on DE - MRI by eyeballing in infarcted myocardium only, and hyper - enhancement was found by machine measure both in hibernating myocardium and infarcted myocardium. But the level of delay enhancement is higher in infarcted myocardium. Conclusion： It can be found hyper - enhancement on DE - MRI both in hibernating myocardium and infarcted myocardium, and DE- MRI is helpful for differential diagnosis between hibernating myocardium with infarcted myocardium.

关 键 词：兔 冬眠心肌 梗死心肌 延迟增强 磁共振成像 

分 类 号：R542.22[医药卫生—心血管疾病] R445.2[医药卫生—内科学]