201^T1显像在良恶性软组织肿瘤诊断中的应用  

AppliGation of 201-Thallium scintigraphy for malignant or benign soft tissue lesions

作　　者：张连娜[1] 彭京京[1] 刘洪洪[2] 杨芳[1] 蔡槱伯[3] 

机构地区：[1]北京积水潭医院核医学科,北京100035 [2]北京积水潭医院病理科,北京100035 [3]北京积水潭医院骨肿瘤科,北京100035

出　　处：《中国医学影像技术》2008年第1期127-130,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨^(201)Tl显像及其半定量分析在软组织良性恶肿瘤诊断中的应用价值。方法回顾性研究骨肿瘤科66例肢体软组织肿瘤及瘤样病变的^(201)Tl显像临床资料,利用ROI技术对其进行半定量分析,所有病例均经手术或病理组织学证实。结果^(201)Tl双时相显像对肢体软组织肿瘤良恶性诊断的灵敏度,特异性和准确性分别为89.2%(33/37)、82.8%(24/29)、86.4%(57/66)。早期相恶性肿瘤组T/NT^e值为3.02±1.74,明显高于良性肿瘤组(1.62±0.84)(P<0.05);延迟相恶性肿瘤组T/NT^d值为2.34±1.28,明显高于良性肿瘤组1.26±0.46(P<0.05)。结论^(201)Tl双时相显像是一种方便、无创的检查方法。在鉴别软组织良、恶性肿瘤的应用方面具有较高的临床诊断价值。Objective To investigate the value of thallium-201-chloride 201^Tl scans and semi-quantitative assessment in the differential diagnosis of soft tissue tumors in extremity. Methods 201^Tl scans was performed in 66 patients with soft tissue tumors. Technique of ROI was used for semi-quantitative assessment. All the cases were confirmed by surgery and histopathological examinations. Results The sensitivity, specificity, and accuracy of 201^Tl scans were 89.2%, 82.8%, and 86.4%, respectively. The early T/NT^e of malignant lesions （3.02±1.74） were higher than benign lesions （1.62±0.84） （P〈0.05）. The delay T/NT^d of malignant lesions （2.3±1. 28） were higher than benign lesions （1.26±0.46） （P〈 0.05）. Conclusion These results support the notion that 201^Tl scintigraphy, although showing some false-positive and false-negative findings, is a useful tool in the evaluation of either malignant tumors or benign lesions.

关 键 词：铊放射性同位素 放射性核素显像 结缔和软组织 肿瘤 单光子发射型计算机断层仪 

分 类 号：R817.4[医药卫生—影像医学与核医学] R73[医药卫生—放射医学]