儿童鲍曼不动杆菌感染情况及其耐药率分析  

Analysis on Acinetobacter Baumannii Infection in Children

作　　者：滕懿群[1] 严霞[1] 陆巧英[1] 吴晓燕[1] 章爱莲[1] 沈定[1] 陆燕[1] 张佩华[1] 

机构地区：[1]浙江省嘉兴市第二医院儿科,314000

出　　处：《中国全科医学》2008年第4期323-325,共3页Chinese General Practice

摘　　要：目的了解儿童鲍曼不动杆菌感染的情况及其对15种抗菌药物的耐药情况。方法对20株鲍曼不动杆菌的临床分布、药敏检测结果进行分析。结果源自气管分泌物、痰、咽拭子标本的鲍曼不动杆菌共16株,占80%;耐药率≥40%的抗菌药物有头孢唑林、氨苄西林、呋喃妥因、氨曲南、头孢曲松、头孢他啶、头孢吡肟,耐药率≤30%的抗菌药物有庆大霉素、环丙沙星、复方磺胺甲口恶唑、妥布霉素、左氧氟沙星、哌拉西林/他唑巴坦、氨苄西林/舒巴坦、亚胺培南;20株鲍曼不动杆菌中多重耐药株共16株,占80%。结论呼吸道是鲍曼不动杆菌的主要来源;鲍曼不动杆菌对抗菌药物已产生多重耐药,应重视该菌感染及耐药性检测情况,预防院内感染发生。Objective To understand the infection of Ac inetobacter baumannii （ A baumannii） in children and make an analysis for its resistance to 15 antibiotics. Methods To segregate and identify the pathogen by BioMerieux microorganism analysis system, drug sensitive is ATB Expression of BioMerieux. Results 16 （80%） A baumannii among 20 isolates come from respiratory tract, The result of drug susceptibility showed that A baumannii was a highly resistant to the β - lactamaseantibiotics, and had a higher susceptibility to aminog lycoside, flnoloaes, Piperacillin/tazobactam, Ampicillin/sulbactam and carbapenems. In 20 stuided strains of A baumannii, multiresistant bacteria accounted for 80% （ 16/20）, 10% （3 kinds antibiotics）, 70% （ 〉 3 kinds） respectively. Conclusion A baumannii strains isolated from children patients showed distinct multiple antibacterial resistance, we must keep an eye out for A baumannii infection and its drug - resistant chang in order to prevent the appearance of nosocomial infections.

关 键 词：鲍曼不动杆菌 儿童 抗菌药物 耐药性 

分 类 号：R378.84[医药卫生—病原生物学]