十二指肠溃疡高选择性迷走神经切断术后胃粘液分泌的研究  

Studies on gastric mucus secretion after highly selective vagotomy in duodenal ulcer patients

作　　者：刘志广[1] 赵禄[1] 盖宝东[1] 李显堂 高天刚 郑扶民[1] 

机构地区：[1]白求恩医科大学第三临床学院基本外科,长春130021 [2]吉林省邮电医院 [3]吉林纸业股份有限公司职工医院

出　　处：《中华实验外科杂志》1997年第4期221-222,共2页Chinese Journal of Experimental Surgery

摘　　要：通过对20例十二脂肠溃疡病人实施高选择性迷走神经切断术(HSV)前后,可视粘液排泌量术后稍降低,与术前比较差异不显著(P>0.05):溶解性粘蛋白排泌量术后降低,与术前比,有显著性差异(P<0.05);溶解性粘 排泌量术后升高.尤其刺激后胃液中升高明显,与术前比差异显著(P<0.05).说明HSV术不明显损害胃粘液屏障.The basic gastric acid output (BAO), maximal gastric acid output (MAO) and three components in basic and pentagastrin-stimulated gastric juice before and after highly selective vagotomy (HSV) in 20 randomized selected duodenal ulcer (DU) patients were determined. The results showed that the contents of BAO and MAO after HSV were lower than before (P<0. 001), the visible mucus output after HSV was decreased with the difference being not significant (P >0. 05). The dissolved mucoprotein output after HSV was markedly decreased as compared with that before HSV (P<0.05), while dissolved mucoproteose output significantly increased after HSV, especially after stimulation,as compared with that before HSV (P<0.05). It is suggested that the obvious reduction in BAO and MAO produced by HSV is similar to those by TV and SV, but HSV didn't damage mucus barrier.

关 键 词：迷走神经切断术 胃粘液 十二指肠溃疡 

分 类 号：R656.620.5[医药卫生—外科学]