鲁中南地区先天性心脏病患者的ABO血型相关性研究  

Study on the Correlativity of ABO Blood Type of the Patients with Congenital Heart Disease in Central Region of South Shandong

作　　者：李大鹏[1] 靳丽[1] 刘文清[1] 王永清[1] 任红[1] 张志勇[1] 王锦庆[2] 

机构地区：[1]解放军第88医院 [2]泰安市中心医院,山东泰安271000

出　　处：《临床军医杂志》2008年第1期79-80,共2页Clinical Journal of Medical Officers

摘　　要：目的研究先天性心脏病发生与ABO血型抗原分布关系。方法选择鲁中南地区先天性心脏病患者444例,采用血型群体遗传学及血型血清学方法,进行ABO血型表现型及基因频率分布调查统计。结果发生先天性心脏病的ABO血型抗原分布与对照组无显著性差异。结论提示发生先天性心脏病与患者ABO血型间无显著相关性关系,血型因素不是重要的先天性心脏病易感因素。Objective To study the correlativity between congenital heart disease and ABO blood type antigen distribution. Methods ABO phenotype and its genetic distribution were investigated in 444 patients with congenital heart disease in center of south region of shandong via blood type genetics and serology. Results No clear difference in ABO blood type antigen distribution was found between the patients with congenital heart disease and the controls, i.e. there was not any significant correlativity between the probability suffering the disease and ABO blood type. Conclusion There is no significant correlativity between congenital heart disease and ABO blood type, so blood type is not an impressionable factor that leads to congenital heart disease.

关 键 词：先天性心脏病 ABO血型 血型抗原 

分 类 号：R541.1[医药卫生—心血管疾病] R457.11[医药卫生—内科学]