外周动静脉同步换血法治疗新生儿高胆红素血症  

Exchange transfusion using peripheral arteries and veins on newborn infants with severe hyperbilirubinemia

作　　者：蔡琍璇[1] 展爱红[1] 赵奕怀[1] 麦隽[1] 林浩铨[1] 

机构地区：[1]汕头市中心医院儿科,广东省汕头515031

出　　处：《中国基层医药》2007年第12期1955-1957,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨外周动静脉同步换血治疗新生儿重症高胆红素血症的疗效、安全性及其对血液内环境的影响。方法对22例重度高胆红素血症新生儿采用经外周动静脉进行同步换血疗法,并对换血前后电解质、血常规、血生化指标及生命体征进行监测。结果本组血清总胆红素换血前、后分别为(595.28±134.44)μmol/L和(275.17±74.05)μmol/L,有明显下降(P<0.01),总胆红素换出率53.77%。换血后血电解质稳定.血糖暂时性升高,可有贫血,白细胞及血小板明显下降.但在24 h内自行恢复至正常。换血过程中心率、呼吸、血氧饱和度无明显波动,无明显并发症发生。结论采用外周动静脉同步换血法具有较高的胆红素换出率.疗效肯定.操怍简便,安全,内环境的影响较小,值得应用及推广。Objeclive To study effectiveness and effect on the internal environment of exchange transfusion using peripheral arteries and veins. Methods Exchange transfusion were performed through the peripheral arteries and veins on 22 cases of newborn infants with severe hyperbilirubinemia. Blood electrolyte,blood routine, blood biochemistry were measured before and after change blood. Vital signs were monitored electronically recorded. Results Total bilirubin was （595.28±134.44）μmol/L before exchange transfusion and （275.17±74.05）μmol/L after exchange transfusion（ P〈 0.01 ）. Total bilirubin clearance rate was 53.77 %. After exchange transfusion, blood elec-trolyte level off. blood glucose rose transitorily. Anemia might occur, leucocyte and blood platelets decreased in number obviously, but blood routine was resumed by self-adjustment after 24 hours. Vital signs were tranquilization. There was no complication. Conclusion Exchange transfusion using peripheral arteries and veins was simple, practi-cable and safe, having less impact on the internal environment.

关 键 词：高胆红素血症 外周动静脉 换血 新生儿 

分 类 号：R722.1[医药卫生—儿科]