基于正交试验与化学子空间法研究中药重楼中甾体皂甙的提取工艺  

Study on extraction of steroidal saponins from Chinese medicine rhizoma paridis based on orthogonal test and chemical subspace method

作　　者：陈雨[1] 陈泽琴[2] 张经硕[1] 蒋雪[1] 谢洪平[1] 

机构地区：[1]苏州大学药学院 [2]西华师范大学化学化工学院,四川南充637000

出　　处：《化学研究与应用》2008年第2期208-211,共4页Chemical Research and Application

基　　金：化学生物传感与计量学国家重点实验室开放基金(2003-16);苏州大学优秀中青年学术带头人基金(R2317043)资助项目

摘　　要：UV analytical method for the extraction liquid of the steroidal saponin from chinese medicine rhizoma paridis has been established by using the chemical subspace invariant to linear transformation method and the characteristics of the UV spectra.Based on the orthogonal test of L16(45),the five factors for the extraction of steroidal saponin from Yunnan rhizoma paridis,including the extraction time,the concentration of ethanol solution and its volumn,the time of heating reflux and the times of extraction,have been optimized according to the extraction ratio.The extraction ratio for the optimized extraction is up to 11.49%.It also has been proved that the time of heating reflux is the most important factor.UV analytical method for the extraction liquid of the steroidal saponin from chinese medicine rhizoma paridis has been established by using the chemical subspace invariant to hnear transformation method and the characteristics of the UV spectra. Based on the orthogonal test of L16 （45 ）, the five factors for the extraction of steroidal saponin from Yunnan rhizoma paridis, including the extraction time, the concentration of ethanol solution and its volumn, the time of heating reflux and the times of extraction, have been optimized according to the extraction ratio. The extraction ratio for the optimized extraction is up to 11.49%. It also has been proved that the time of heating reflux is the most important factor.

关 键 词：重楼 甾体皂甙 实验设计 化学子空间比较法 

分 类 号：O629.26[理学—有机化学]