1069例冠心病患者冠状动脉造影与中医证候特点  

Characteristics of coronary arteriography and traditional Chinese medicine syndrome of 1 069 patients with coronary artery disease

作　　者：王阶[1] 邢雁伟[1] 陈建新[2] 何庆勇[1] 高永红[3] 李尊[1] 

机构地区：[1]中国中医科学院广安门医院心内科,北京100053 [2]中国科学院自动化研究所复杂系统与智能科学重点实验室,北京100080 [3]北京中医药大学东直门医院重点实验室,北京100700

出　　处：《中西医结合学报》2008年第2期148-152,共5页Journal of Chinese Integrative Medicine

基　　金：国家重点基础研究发展规划973项目(No.2003CB517103);国家中医药管理局课题(No.02-03JP47);国家自然科学基金重大计划面上项目(No.90209011)

摘　　要：目的:研究冠心病冠状动脉造影和中医证候特点。方法:用临床流行病学方法调查1069例冠心病患者,按发病年龄分青年组(82例,年龄≤45岁)和中老年组(987例,年龄>45岁),分析两组患者临床资料及冠状动脉病变和中医证候特点。结果:青年组男性比例、甘油三酯、总胆固醇、吸烟人数、发生急性心肌梗死比例和冠心病家族史显著高于中老年组(P<0.05)。中老年组伴发高血压和糖尿病的病例高于青年组(P<0.05)。中老年组冠脉造影检查,左主干、回旋支和多支病变的发病率显著高于青年组(P<0.05)。青年组单支病变和双支病变的发病率显著高于中老年组(P<0.05)。青年冠心病组中气滞、痰浊的比例显著高于中老年组(P<0.05),而中老年组的寒凝、阳虚、阴虚和肾虚的比例显著高于青年组(P<0.05)。结论:青年冠心病心绞痛中医证候和冠脉病变有自身的特点而区别于老年冠心病。Objective：To study the characteristics of coronary arteriography and traditional Chinese medicine syndrome of 1 069 patients with coronary artery disease（CAD）.Methods：One thousand and sixty-nine patients with CAD were investigated by epidemiological method.The patients were divided into young patients（n=82,aged 45 years or younger）and middle-aged and old patients（n=987,older than 45 years）.The characteristics of the two groups were analyzed,including clinical data,coronary arteriography and traditional Chinese medicine syndrome.Results：Compared with middle-aged and old patients,proportion of male,triglyceride,total cholesterol,smoking patients,acute myocardial infarction and family history of CAD in young patients were significantly higher（P〈0.05）.Patients accompanying with hypertension and diabetes in middle-aged and old patients were more than those in young patients（P〈0.05）.Occurrence rates of morbidity of left circumflex coronary artery,left main coronary artery and multi-branch were higher in middle-aged and old patients（P〈0.05）,however,the occurrence rates of morbidity of single and double-branch were higher in young patients（P〈0.05）.The occurrence rates of syndromes of qi stagnation and phlegm turbidity in young patients were higher than those in middle-aged and old patients（P〈0.05）.But the proportions of cold coagulation,yin deficiency,yang deficiency and kidney deficiency in middle-aged and old patients were obviously higher（P〈0.05）.Conclusion：The traditional Chinese medicine syndrome and pathological changes of CAD in young patients are different from those in old patients.

关 键 词：冠状动脉心脏病 冠状动脉造影术 证候 青年 

分 类 号：R259[医药卫生—中西医结合]