红光照射对动物肝脏、骨骼肌和血液中ATP含量变化的影响  

Effects of radiation with red light on ATP contents in rabbits' liver,skeletal muscle and blood

作　　者：贾丹兵[1] 李乃民[1] 唐立明[1] 于农[1] 刘珊[1] 王正雷[1] 卢宇[1] 张永丰[1] 孙旗立[1] 

机构地区：[1]解放军第211医院,哈尔滨150080

出　　处：《解放军医学杂志》2007年第12期1286-1287,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：目的通过观察红光照射后动物肝脏、骨骼肌及血液中ATP含量的变化,研究红光照射对抗疲劳能力和耐力的影响。方法大耳白兔18只,随机分为对照组(A组)、红光照射1周组(B组)和红光照射2周组(C组),每组6只。A组不接受红光照射,B组和C组分别接受红光照射1周和2周,每天1次,每次3h。处理完毕后采动物耳血,并在全麻下切取肝脏及骨骼肌,检测血、肝脏和骨骼肌内的烟酰胺腺嘌呤二核苷酸(NAD)、一磷酸腺苷(AMP)、二磷酸腺苷(ADP)、三磷酸腺苷(ATP)含量。结果与对照组相比,实验组动物血液、肝脏和骨骼肌内的NAD、AMP、ADP、ATP含量均明显增高。结论红光照可明显提高肝脏及骨骼肌内ATP及其相关因子的含量,增加ATP的合成,从而能有效提高机体的抗疲劳能力。Objective The study is aimed to investigate the effects of radiation with red light on ATP contents in animals＇ liver,skeletal muscle and blood,and further to surmise the effects of the radiation on surmounting the exercise-induced fatigue.Methods 18 French white rabbits,weighed 2.0±0.5 kg,were randomly assigned to 3 groups with 6 animals for each：the animals in group A acted as control with no treatment by red light radiation,in groups B and C the animals received radiation with red light once a day and 3 hours for each time,the treatment for group B continued for one week and for group C continued for 2 weeks.Once the treatment of red light radiation ended,the venous blood were collected from the ear edge and the animals were executed,the liver tissue and skeletal muscle samples were collected,and then the contents of nicotinamide adenine dinucleotide（NAD）,adenosine monophosphate（AMP）,adenosine diphosphate（ADP）and adenosine triphosphate（ATP）in the samples were detected.The same collection and detection of samples were also done for the control animals.Results Compared to control group,the levels of NAD,AMP,ADP and ATP in blood samples,liver tissues and skeletal muscles in both groups B and C were significantly higher after red light radiation for certain period.Conclusion Red light radiation is one of the widely-used biotherapies with such advantages as harmless,acceptable,effectiveness on relieving pains,tension and nervousness,for its capability of inducing beneficial bio-reactions in the subcutaneous,muscular and skeletal muscles with possible improvement of exercise-induced fatigue and endurance.Since ATP serves as a key factor in supplying energy for the body and supporting basic cellular respiration,and red light radiation may increase the ATP contents in blood,tissue and muscular,so the radiation may improve the ability of anti-fatigue.

关 键 词：红光 腺苷三磷酸 肝 肌 骨骼 

分 类 号：R454.29[医药卫生—治疗学]