兴安黄芪化学成分研究  

Studies on chemical constituents of Astragalus Dahuricus

作　　者：王金兰[1] 许红梅[1] 李卫宏[2] 华准[1] 张树军[1] 

机构地区：[1]齐齐哈尔大学化学与化学工程学院,黑龙江齐齐哈尔161006 [2]大庆师范学院化学与化工系,黑龙江大庆163712

出　　处：《中国中药杂志》2008年第4期414-416,共3页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金委与日本学术振兴会联合合作项目(20175027)

摘　　要：目的:研究兴安黄芪的化学成分。方法:用硅胶柱色谱、重结晶及半制备HPLC进行分离纯化,根据理化性质和光谱数据进行结构鉴定。结果:得到6个单体化合物,分别为7,2′-二羟基-3,′4′-二甲氧基异黄烷(1),2′-羟基-3,′4′-二甲氧基异黄烷-7-O--βD-葡萄糖苷(2),8,2′-二羟基-7,4′-二甲氧基异黄烷(3),7-羟基-4′-甲氧基异黄酮(4),7,3′-二羟基-4′-甲氧基异黄酮(5),9,10-二甲氧基紫檀烷-3-O--βD-葡萄糖苷(6)。结论:这些化合物均系首次从该植物中得到。Objeettive： To study the chemical constituents in Astragalus dahuricus. Method： The compounds were isolated and purified by column chromatography on silica gel and HPLC, and their structures were elucidated by their spectroscopic evidences. Result： Six compounds were identified as： 7, 2＇-dihydroxy-3＇, 4＇-dimethoxyisoflavan （1）, 2＇-hydroxy-3＇, 4＇-dimethoxyisoflavan-7-O-β-D-glucopyranoside （2）, 8, 2＇-dihydroxy-7, 4＇-dimethoxyisoflavan （3）, 7-hydroxy-4＇-methoxyisoflavone （4）, 7, 3＇-dihydroxy-4＇- metho-xyisoflavone （5） , 9, 10-dimethoxypteroearpan-3-O-β-D-glueopyranoside （6）. Conclusion： Compounds 1-6 were obtained from this olant for the first time.

关 键 词：兴安黄芪 异黄酮 异黄烷 紫檀烷 

分 类 号：R284[医药卫生—中药学]