苯并氮杂冠醚-15-冠-5 Schiff碱钴(Ⅱ)配合物催化PNPP水解研究  

Studies on PNPP hydrolysis catalyzed by schiff base cobalt(Ⅱ) complexes containing Benzoaza-15-crown-5

作　　者：胡伟[1] 李建章[1] 

机构地区：[1]四川理工学院化学系,自贡643000

出　　处：《四川大学学报（自然科学版）》2008年第1期147-150,共4页Journal of Sichuan University(Natural Science Edition)

基　　金：四川省教育厅重点项目(2005D007)

摘　　要：在pH7.0和25℃下,研究了三种带有苯并氮杂冠醚-15-冠-5侧基的Schiff碱钴(Ⅱ)配合物CoL1,CoL2和CoL3,作为模拟水解金属酶催化羧酸酯水解的作用.通过对水解反应体系的特性吸收光谱的分析,提出了PNPP的催化水解的机理,并在此机理上建立了PNPP催化水解的动力学数学模型.讨论了三种Co(Ⅱ)配合物催化水解PNPP的性能.Three Schiff base cobalt（ Ⅱ ） complexes containing benzoaza-15-crown-5, CoL^1, CoL^2 and CoL^3 were used in catalytic hydrolysis of carboxylic ester （PNPP, p-nitrophenyl picolinate） as mimic hydrolytic metalloenzyme at pH 7.0 and 25℃. The mechanism of PNPP catalytic hydrolysis has been proposed based on the analytic result of specific absorption spectrum of reaction systems. A kinetic mathematical model, applied to the calculation of the kinetic parameter of PNPP catalytic hydrolysis, has been established based on the mechanism proposed. The behaviour of the three Cobat（ Ⅱ） complexes catalyzing PNPP hydrolysis has been discussed in this paper.

关 键 词：冠醚Schiff碱钴(Ⅱ)配合物 模拟水解酶 动力学 羧酸酯 

分 类 号：O643[理学—物理化学]