左心辅助对全心缺血心脏右心室功能的影响  

The Assist Effect of LVAD on Right Ventricular Function in Global Injured Canine Heart

作　　者：陈长城[1] 陈宝田[1] 王盛宇[1] 何美玲[1] 杜月河[1] 

机构地区：[1]北京安贞医院心脏外科

出　　处：《中华胸心血管外科杂志》1997年第4期240-242,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：为评价左心辅助对全心缺血损害心脏右室功能的影响，利用转子泵经左心房至升主动脉对７只心衰犬行左心辅助１８０分钟。采用心脏常温缺血１０分钟的方法（阻断升主动脉）制作心衰模型。结果显示：（１）辅助过程中平均动脉压能维持在８ｋＰａ（６０ｍｍＨｇ）水平，心排量增加（Ｐ＜０．０１），心排指数上升（Ｐ＜０．０５），右室收缩舒张性能改善，右心室每分作功指数增加。（２）心肌能量物质ＡＴＰ含量增加。结论：左心辅助可改善全心缺血心脏右室功能。Objective:To evaluate the assist effect of left heart bypass with LVAD on right ventricular function in heart failure produced by global ischemia.Method:The heart in 7 dogs was subjected to global ischemia by aortic cross clamping for 10 minutes at 37℃.The left heart was partially assisted by left atrial appendage to ascending aorta bypass using roller pump for 180 minutes.Results:The mean aortic pressure could be maintained at 60 mmHg,cardiac output and cardiac index increased significantly(P<0.01 and P<0.05 respectively).Myocardial ATP content showed slight recovery.Conclusion:Left heart assistance can improve right heart function in heart failure resulting from global ischemic injury in dogs.

关 键 词：左心辅助 全心缺血 右心室功能 

分 类 号：R541.4[医药卫生—心血管疾病]