338例孕妇风疹病毒感染调查  

Investigation on 338 cases Pregnamcy Infected RubeUa Virus

作　　者：徐小仁[1] 张凌玲[2] 曾嫦[1] 黄宇泽[1] 谢若男[1] 

机构地区：[1]广东省汕头市中心医院检验科,广东汕头515031 [2]汕头大学第一附属医院检验科,广东汕头515031

出　　处：《河北医学》2008年第1期53-55,共3页Hebei Medicine

摘　　要：目的:探讨风疹病毒(RV)感染与孕妇流产、死(畸)胎的关系。对338例孕妇和60例对照者RV感染状态进行了调查分析。方法:应用酶联免疫吸附试验(ELISA)检测RV-IgM和IgG特异性抗体。结果:RV-IgM和IgG抗体阳性率流产组220阳性142例,阳性率64.5%〔IgM阳性率7.3%(16/220),IgG阳性率57.3%(126/220)〕,死(畸)胎118例,阳性80例,阳性率67.8%〔IgM阳性率10.2%(12/118)IgG阳性率57.6%(68/118)〕,对照组60例,IgG阳性18例,阳性率30.0%。患者组与对照组IgG阳性率比较差异非常显著(P<0.001)。结论:RV感染是导致孕妇死(畸)胎和流产有关。Objective：To investigate the relationship between rubella virus （ RV ） infection and miscarriage, and fetal death（ terata） as well, 338 cases of pregnancy termination and 60 healthy pregnancy cases as a control group were compared and analyzed. Method： The IgM and IgG specific antibody to RV were detected by the ELISA method. Resulet：The positive rate of these two specific antibodies are 64.5% （ 142/220 ） , 67,8% （80/118） and 30.0% （ 18/60） for miscarriage group, fetal death（ terata） group and health control group respectively. The heterogeneity of the positive rate between patient group and control group has statistically significance （P 〈 0.001 ） Conclusion： These results indicate RV infection is highly correlated with miscarriage and fetal death for pregnancy.

关 键 词：风疹病毒感染 流产 死(畸)胎 ELISA抗体 

分 类 号：R714.2[医药卫生—妇产科学]