臭氧联合复方倍他米松注射治疗腰椎间盘突出症  

Clinical study of percutaneous injection of intradisc and intervertebral foramen with ozone and betamethasone compound to treat lumbar disc herniation

作　　者：陈富强[1] 胡丹[1] 时飞[1] 谢平[1] 艾登斌[1] 

机构地区：[1]青岛市市立医院麻醉科疼痛病房,山东青岛266011

出　　处：《颈腰痛杂志》2008年第1期27-29,共3页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的比较臭氧椎间盘内注射联合复方倍他米松椎间孔注射治疗腰椎间盘突出症的临床疗效。方法经CT或MRI诊断为腰椎间盘突出症的患者64例,按入院前后顺序随机入组。对照组31例单纯椎间盘内注射臭氧。试验组33例采用椎间盘内注射臭氧,联合复方倍他米松椎间孔注射。临床疗效采用MacNab评分及VAS评分,分别评价术后1d、5d,电话随访3个月疗效。结果术后1d、5d的有效率分别为:试验组:96.97%,93.94%,对照组:77.19%、74.19%。组间比较差异有显著性(P<0.05)。术后3个月的有效率为试验组87.88%,对照组80.65%,组间比较差异无显著性(P>0.05)。结论臭氧盘内联合复方倍他米松椎间孔注射可以加速腰腿疼痛症状的改善,提高腰椎间盘突出症的近期疗效。Objective To evaluate the difference of intradiscal and intervertebral foramen injection with ozone and betamethasone compound to treat lumbar disc herniation about the short-term clinical effects. Methods 64 patients with the symptoms of sciatica and low back pain were selected and divided in two groups randomly,including 28 cases with disc bulging,36 protrusion diagnosed by CT or MRI. control group（31 cases）were intradiscal and intervertebral foramen injected with ozone only and study group（33 cases）were intradiscal and intervertebral foramen injected with ozone and betamethasone compound. The clinical results were assessed separately according to improved Macnab method and VAS lday,5 days,3 months after treatment. Results The excellent and good rate of the two groups were 96.97%,93.94%and77.19%,74.19% respectively at 1 clay and 5 clay after treatment,which has a statistical difference（P〈0.05）. The excellent and good rate of the two groups was 87.88% and 80.65% respectively at 3 months after treatment,which has no statistical difference （P〉0.05）. Conchlsion The method of ozone and betamethasone compound injection into lumbar intervetebral disc and foramen is a effective method for the treatment of the lumbar disc herniation. It improves the pain reief and the short-term clinical effects.

关 键 词：腰椎 椎间盘移位 椎间盘化学溶解术 臭氧 复方倍他米松 

分 类 号：R681.53[医药卫生—骨科学] O613.3[医药卫生—外科学]