雾化吸入抗结核药治疗开放型肺结核疗效观察  

Clincal Research on Aerosolizing Inhalation Recombinated Antituberculosis Medicine in the Treatment of Pulmonary Tuberculosis Patients with Sputum Smear Positive

作　　者：严勤[1] 李先慧[1] 那琳琳[1] 王莹[1] 

机构地区：[1]哈尔滨二四二医院,黑龙江哈尔滨150066

出　　处：《哈尔滨医药》2008年第1期21-21,24,共2页Harbin Medical Journal

摘　　要：目的观察和评价雾化吸入抗结核药治疗开放型肺结核疗效。方法将我科近两年收治的确诊为双或单肺浸润型结核痰涂阳性者约43人，随机分成观察组和对照组。观察组21例除常规给予化疗药物外还给予应用氧驱动的雾化吸入异烟肼注射液0．1g，链霉素0．25g加入生理盐水20ml，氧流量为5L／m^3 3，每天2次，每次持续15～20分钟，共用20天。对照组只应用一般的抗结核药。结果观察组治疗1个月、2个月和3个月的痰涂阴转率，咳嗽症状缓解和消失率及肺部病灶吸收好转速度均明显优于对照组。结论雾化吸入抗结核药治疗开放型肺结核疗效显著。Objective To explore the therapeutic effect in the treatment of pulmonary tuberculons patients with sputum smears acid fast stain positive. Methods 43 pulmonary tuberculosis patients with sputum smnear positive were divided into two groups at random . Treatment group （21cases） and control group（22cases）. The former were aerosolized isoniazid 0.1 g and amikacin 0.2g twice a day for 20 days. All the patients were given antituberculosis therapy. Results The rate of sputum smear negative conversion , the rate of symptom Of cough and cheat pain and the rate of regain in X - ray about TB are more high than control groups. Conclusion The therapeutic effect in the treatment of pulmonary tuberculons patients with sputum smears acid fast stain positive is obvious. This therapy may be applied in clinic.

关 键 词：雾化吸入 肺结核 痰涂阳 

分 类 号：R521[医药卫生—内科学]