血浆脑利钠肽水平与急性冠脉综合征预后关系的探讨  

Correlation between serum brain natriuretic peptide and acute coronary syndrome

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作  者:郑继平[1] 陈自力[1] 赵旭[1] 

机构地区:[1]台州市第一人民医院心内科,浙江台州318020

出  处:《心血管康复医学杂志》2008年第1期44-45,共2页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘  要:目的:探讨脑利钠肽(BNP)水平与急性冠状动脉综合征(ACS)预后的关系。方法:2005年2月~2007年8月所有入选158例ACS患者均检测入院后48h内及2周后的血浆BNP水平。根据住院期间不良心血管事件的出现而分成不良心血管事件组(62例)和无不良心血管事件组(96例),比较两组入院48hBNP(BNP1)、2周后BNP(BNP2)、2周BNP变化幅度值(ΔBNP%=(BNP1-BNP2)/BNP1×100%)。结果:有不良心血管事件组的BNP1、BNP2水平显著高于无不良心血管事件组(P<0.01),而ΔBNP%低于无不良心血管事件组,说明无不良心血管事件者恢复得较快。结论:BNP是评价ACS预后重要指标之一。Objective: To study the correlation between serum brain natriuretic peptide (BNP) and acute coronary syndrome (ACS). Methods: A total of 158 ACS patients were divided into complicated with cardiovascular event group (group A, 62 cases) and no complicated with cardiovascular event group (group)3, 96 cases). The serum BNP contents were measured on 24h (BNP1) and two weeks (BNP2) after admission in all ACS patients and compared between two groups. Results: The BNP1 and BNP2 of group A were more than those of group B (P〈0.01), but difference value (ABNP%) between BNP1 and BNP2 of group A was less than that of group B (P〈0.01). Conclusion: Level of serum brain natriuretic peptide is a significant index predicting prognosis.

关 键 词:冠状动脉疾病 预后 利钠肽  

分 类 号:R541.409[医药卫生—心血管疾病]

 

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