深圳市2005～2006年健康人群脑膜炎奈瑟菌带菌调查  

Survey of prevalence of Neisseria meningitidis in heathy population in Shenzhen City in 2005 and 2006

作　　者：鞠长燕[1] 黄文繁[1] 俞慕华[1] 刘鸿钧[1] 段永翔[1] 

机构地区：[1]深圳市南山区疾病预防控制中心,广东深圳518054

出　　处：《中国热带医学》2008年第1期80-81,共2页China Tropical Medicine

基　　金：深圳市科技计划项目(200505260331A)

摘　　要：目的了解2005—2006年深圳市健康人群脑膜炎奈瑟菌（Nm）的带菌状况，为制定有效的防制方案提供依据。方法将健康人群分为0-、5-、10-、15-、25-、35-和45-岁以上7个年龄组，采集咽拭子，进行Nm培养分离和鉴定，用血清学诊断和PCR方法分群。结果2005—2006年深圳市健康人群Nm带菌率为4．4％（55／1255），其中B群49株（89．1％），c群4株（7．3％），29E2株（3．6％）。在两次流脑疫情中各分离到1株B群Nm。结论2005—2006年深圳市健康人群主要携带B群Nm，未检出A群Nm，A群流脑传染源较少。Objective To understand the Neisseria meningitidis - carrying rate in healthy people of Shenzhen City. Methods Throat swabs were collected from healthy people of various age groups in Shenzhen and Neisseria meningitidis was isolated. Results Neisseria meningitidis were isolated from 55 swabs giving an overall carrying rate of 4.4%, in which 49 （3.9%） isolatesbelonged to serngroup B,4（0.3% ） isolates beonged to serogroup C, 2（0.2% ） isolates belonged to serogroup29E. 2 more strains were isolated from one patient and one close contact. Conclusion Serngroup B is the main serogroup carried by healthy people and no serogroup A cartier is found, indicating that there is few source of serogroup A meningococcal infection.

关 键 词：流行性脑脊髓膜炎 脑膜炎奈瑟菌 带菌调查 

分 类 号：R378.15[医药卫生—病原生物学]