舒芬太尼与瑞芬太尼用于儿童扁桃体和腺样体切除术后麻醉恢复质量的比较  

Comparison of early postoperative recovery quality between Sufentanil and Remifentanil for children undergoing adenotonsillectomy

作　　者：王少婕[1] 张炳熙[1] 

机构地区：[1]首都医科大学附属北京同仁医院麻醉科,100730

出　　处：《中国现代医药杂志》2008年第2期13-15,共3页Modern Medicine Journal of China

摘　　要：目的观察舒芬太尼与瑞芬太尼在儿童扁桃体和腺样体切除术中及术后镇痛镇静作用,比较两种药物对麻醉恢复质量的影响。方法选择择期进行扁桃体和腺样体切除术患儿80例,随机分为舒芬太尼组(S组,n=40)和瑞芬太尼组(R组,n=40)。S组以舒芬太尼0.2μg/kg快速诱导,以0.2μg·kg-1·h-1术中维持,手术结束前30分钟停药。R组以瑞芬太尼2μg/kg快速诱导,以6μg·kg-1·h-1术中维持,手术结束前5分钟停药。分别观察两组术中术后血流动力学指标及术后患儿镇痛镇静程度。结果两组在术中血流动力学指标无明显差异(P>0.05)。拔管后5分钟时S组MAP较基础值无明显差异;R组MAP较基础值明显增高(P<0.05)。S组患儿在术后Ramsay评分较适宜,VAS评分较低。结论两种药物均适用于儿童扁桃体和腺样体切除术,舒芬太尼可提高术后麻醉恢复质量。Objective To observe the analgesic effects of sufentanil and remifentanil in operative procedure and early postoperaive period for children undergoing adenotonsillectomy and to evaluate the effects of the two analgesic drugs on the early postoperative recovery quality. Methods Eighty children undergoing adenotonsillectomy were randomly divided into two groups： sufentanil（group S,n=40） and remifentanil （group R,n=40）. VAS and Ramsay score, MAP,HR and SPO2 were measured during anesthesia and postoperation. Results There were no statistical differences on hemodynamic parameters between the two groups during operative procedure（P〉0.05）. There was significant difference on MAP after extubation in group R. Whereas in group S, the MAP after extubation was similar. Conclusion Sufentanil and remifentanil are safe and effective for children undergoing adenotonsillectomy. Sufentanil is better to remifentanil for the postoperative recovery quality.

关 键 词：扁桃体和腺样体切除术 舒芬太尼 镇痛 镇静 恢复质量 

分 类 号：R726.1[医药卫生—儿科]