^(201)TlCl注射液中铊载体的分光光度测定  

SPECTROPHOTOMETRIC DETERMINATION OF Tl CARRIER IN 201 Tl TlCl INJECTION

作　　者：弓全胜[1] 景烈[1] 

机构地区：[1]中国原子能科学研究院同位素研究所

出　　处：《核化学与放射化学》1997年第2期57-60,共4页Journal of Nuclear and Radiochemistry

摘　　要：研究了分光光度法测定２０１ＴｌＣｌ注射液中载体铊的含量。用溴水作氧化剂，将Ｔｌ（Ⅰ）氧化为Ｔｌ（Ⅲ），并加入磺基水杨酸除去过量溴，以对硝基苯重氮氨基偶氮苯（简称镉试剂）为显色剂，聚乙二醇辛基苯基醚（乳化剂ＯＰ）为胶束增溶剂在水相中直接测定Ｔｌ（Ⅲ），显色体系为ｐＨ＝１１．７的ＮＨ４Ｃｌ－ＮＨ４ＯＨ缓冲溶液，配合物的最大吸收波长为４６９ｎｍ，摩尔吸光系数为１．３７×１０４ｍ２／ｍｏｌ。A simple and sensitive method for the spectrophotometric determination of carrier content (Thallium) in 201 Tl TlCl injection is described.Thallium(Ⅰ) is oxidised to Thallium(Ⅲ) by aqueous bromine,then excess bromine is removed by adding sulfosalicylic acid.In buffer solution (NH 4Cl NH 4OH) at pH 11 7 with the presence of emulsifer OP,thallium(Ⅲ) and ladion form a complex having an absorption maximum at 469 nm with a molar absorptivity of 1 37×10 4 m 2/mol. Beer′s law is obeyed in the concentration range of 0—7 μg/5 mL.The effect of impurity elements in 201 Tl TlCl injection is examined.It is an ideal method for the analysis of radioactive solution.

关 键 词：铊载体 分光光度法 铊201 显像剂 注射液 

分 类 号：R817.9[医药卫生—影像医学与核医学]