一种色谱保留模型的改进及二茂铁衍生物保留值的预测  

Improvement of the Retention Model in Reversed Phase-High Performance Liquid Chromatography and Prediction of the Retention of Ferrocene Derivatives

作　　者：王善韦[1] 李延东 杨学谨[1] 师树简[2] 

机构地区：[1]南开大学中心实验室,化学系天津300071 [2]北京化工学院化学系,北京100031

出　　处：《分析化学》1997年第3期341-344,共4页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金

摘　　要：二茂铁衍生物在四氢呋喃－甲醇－水三元溶剂系统中的保留符合Ｋｏｗａｌｓｋａ所提出的 物理化学保留模型１。但由于模型１没有考虑到化学计量问题，故其结果不够精确。本文在模 型１中引入粘度系数（或介电常数）来定量表示化学计量关系，得到明显优于模型１的模型 ２。鉴于ＨＰＬＣ系统中常以ｌｏｇＫ’表示保留值，本文以ｌｏｇＫ’代替模型１、２中的Ｒｆ值，简化了 计算。The retention values of ferrocene derivatives in THF-MeOH-H2O ternary solvent system were coinsided with the physico-chemical retention model 1 of Kowalska T. Howev- er, Model 1 does not consider the chemical stoichiometry and its conclusion is not so exact e- nough. Our work introduced viscosity coefficient (or dielectric constant) to express the quantitative chemical correlation, so we obtained Model 2 better than model l. Usually HPLC systems use logk' to stand for retention value. In this paper. logk' is used to stand for Rf values of Model 1 and 2 so as to simplify the calculation.

关 键 词：反相 高效液相色谱 二茂铁衍生物 保留值 

分 类 号：O657.7[理学—分析化学] O627.81[理学—化学]