普卢利沙星片溶出度测定方法研究  

Study on dissolution test of prulifloxacin tablets

作　　者：郭毅[1] 付焱[2] 

机构地区：[1]河北省药品检验所,石家庄050011 [2]河北医科大学新药开发研究室,石家庄050017

出　　处：《药物分析杂志》2008年第2期321-322,共2页Chinese Journal of Pharmaceutical Analysis

摘　　要：目的:建立紫外分光光度法测定普卢利沙星片溶出度。方法:以0.1 mol·L^(-1)盐酸作为溶剂,测定波长274 nm。结果:线性范围为1～10μg·mL^(-1),r=0.9999,平均回收率为100.0%(n=9)。结论:本方法简便,结果准确。Objective：To establish a ultraviolet spectrophotometry Prulifloxacin Tablets. Methods：0. 1 mol · L^-1 HCl as dissolution The linearity of calibration curve was in the range of 1 - 10 p.g method for the determination of dissolution test of medium, and the detection at 274 nm. Results： The linearity of calibration curve was in the range of 1 - 10 μg · mL^-1 , and the correlation coefficient was r = 0. 9999. The average recovery was 100. 0% （ n = 9）. Conclusion： The method is easy to operate and the results of the determination is accurate.

关 键 词：普卢利沙星 紫外分光光度法 溶出度 

分 类 号：R917[医药卫生—药物分析学]